M 型光声粒子流成像
M-mode photoacoustic particle flow imaging.
作者信息
Fang Hui, Wang Lihong V
机构信息
Optical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.
出版信息
Opt Lett. 2009 Mar 1;34(5):671-3. doi: 10.1364/ol.34.000671.
Abstract
Recently, there has been growing interest in the development of photoacoustic flow measuring methods aimed to study microvascular blood flow in biological tissue. Here, we describe the M-mode photoacoustic particle flow imaging, using an optical resolution photoacoustic microscope equipped with a high-repetition-rate pulsed dye laser. We studied the flow of a diluted dyed particle suspension in a small tube embedded in a nonscattering medium as well as in a scattering medium simulating biological tissue. Potentially, the method can be applied to detect the flow speed of single red blood cells in a capillary.
摘要
最近，人们对旨在研究生物组织中微血管血流的光声血流测量方法的开发越来越感兴趣。在此，我们描述了一种M模式光声粒子流成像技术，它使用配备了高重复率脉冲染料激光器的光学分辨率光声显微镜。我们研究了稀释的染色颗粒悬浮液在嵌入非散射介质以及模拟生物组织的散射介质中的小管中的流动情况。该方法有可能用于检测毛细血管中单个红细胞的流速。
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