体内光学编码光声血流成像术。

Zhang Ruiying, Wang Lidai, Yao Junjie, Yeh Cheng-Hung, Wang Lihong V

Opt Lett. 2014 Jul 1;39(13):3814-7. doi: 10.1364/OL.39.003814.

We present an optically encoded photoacoustic (PA) flow imaging method based on optical-resolution PA microscopy. An intensity-modulated continuous-wave laser photothermally encodes the flowing medium, and a pulsed laser generates PA waves to image the encoded heat pattern. Flow speeds can be calculated by cross correlation. The method was validated in phantoms at flow speeds ranging from 0.23 to 11 mm/s. Venous blood flow speed in a mouse ear was also measured.

我们提出了一种基于光学分辨率光声显微镜的光学编码光声（PA）血流成像方法。强度调制连续波激光对流动介质进行光热编码，脉冲激光产生光声波以对编码的热模式进行成像。血流速度可通过互相关计算得出。该方法在流速范围为0.23至11毫米/秒的体模中得到了验证。还测量了小鼠耳部的静脉血流速度。