Cormier Y, Boulet L P, Bedard G, Tremblay G
Unité de Recherche, Centre de Pneumologie de l'Hôpital Laval, Quèbec, Canada.
Scand J Work Environ Health. 1991 Aug;17(4):269-75. doi: 10.5271/sjweh.1703.
Swine building workers (N = 488) and nonfarming neighborhood referents (N = 216) were enrolled in this study. There was a slight but significant increase in the prevalence of chronic bronchitis (17.49 versus 11.57%) and more evidence of airflow obstruction (forced expiratory volume in 1 s/forced vital capacity 0.75 versus 0.78) among the swine workers when they were compared with the referents. The subjects who spent more than 3 h/d in the swine buildings had a higher prevalence of chronic bronchitis (21.94 versus 13.25%) and airflow obstruction (forced expiratory volume in 1 s/forced vital capacity 0.75 versus 0.76) than those with shorter daily contact. Swine building only workers had no precipitins to antigens found in their environment and no clinical evidence of extrinsic allergic alveolitis. The number of years on the farm, dual exposure with dairy cattle, positive skin prick tests, type of piggery, and type of feeding did not add to the respiratory health impact of swine buildings.
本研究纳入了养猪场工人（N = 488）和非农业社区对照人群（N = 216）。与对照人群相比，养猪场工人慢性支气管炎的患病率略有但显著升高（17.49% 对 11.57%），气流受限的证据更多（第1秒用力呼气量/用力肺活量为0.75对0.78）。每天在猪舍中停留超过3小时的受试者，其慢性支气管炎的患病率（21.94% 对 13.25%）和气流受限（第1秒用力呼气量/用力肺活量为0.75对0.76）高于每日接触时间较短的受试者。仅在猪舍工作的工人对其环境中发现的抗原无沉淀素，也无外源性过敏性肺泡炎的临床证据。在农场工作的年限、与奶牛的双重接触、皮肤点刺试验阳性、养猪场类型和饲养方式并未增加猪舍对呼吸健康的影响。
