Donham K, Haglind P, Peterson Y, Rylander R, Belin L
Institute of Agricultural Medicine and Occupational Health, University of Iowa, Iowa City 52242.
Br J Ind Med. 1989 Jan;46(1):31-7. doi: 10.1136/oem.46.1.31.
The relation between the health of workers and the environment in swine confinement buildings was investigated in a study of 57 workers on 30 swine farms in southern Sweden and 55 matched controls. Swine workers reported significantly higher frequencies of respiratory symptoms, more frequent colds and absence due to chest illness, and a history of pneumonia. The increased frequency of symptoms of respiratory disease was related to the number of years and percent of the day spent working with swine. Symptoms were also associated with respirable dust, total dust, endotoxin in total dust, and number of microbes in the air of the work environment. In a multiple regression analysis of the relation between 16 different environmental parameters to work period shifts of five pulmonary function parameters, endotoxin was found to be significantly related to the FEV1 in a dose dependent way.
在瑞典南部30个养猪场对57名工人及55名配对对照进行的一项研究中，调查了密闭猪舍中工人健康与环境之间的关系。养猪工人报告的呼吸道症状出现频率显著更高，感冒更频繁，因胸部疾病缺勤的情况更多，且有肺炎病史。呼吸系统疾病症状出现频率的增加与从事养猪工作的年限和每天工作时间的百分比有关。症状还与可吸入粉尘、总粉尘、总粉尘中的内毒素以及工作环境空气中的微生物数量有关。在对16种不同环境参数与五项肺功能参数的工作时段变化之间关系的多元回归分析中，发现内毒素与第一秒用力呼气容积呈显著的剂量依赖性关系。
