Wakkee Marlies, Nijsten Tamar
Department of Dermatology, Erasmus Medical Centre, PO Box 2040, 3000 CA Rotterdam, The Netherlands.
Dermatol Clin. 2009 Apr;27(2):137-47, vi. doi: 10.1016/j.det.2008.11.013.
Recently, comorbidities have been rediscovered in dermatology. Although numerous associations between skin diseases and other conditions have been reported, only a few are well documented. The association of comorbidities and dermatoses is complex and multifactorial. Life-style factors, impaired health-related quality of life, depression, therapeutic interventions, and several biases may confound the relationship between skin diseases and comorbidities. This article discusses observational studies that assess comorbidities in psoriasis, atopic dermatitis, vitiligo, and nonmelanoma skin cancer, and the likelihood of the observed associations and their clinical consequences.
最近，共病现象在皮肤病学领域重新受到关注。尽管已有大量关于皮肤病与其他疾病之间关联的报道，但仅有少数有充分的文献记载。共病与皮肤病之间的关联复杂且具有多因素性。生活方式因素、健康相关生活质量受损、抑郁、治疗干预以及多种偏差可能会混淆皮肤病与共病之间的关系。本文讨论了评估银屑病、特应性皮炎、白癜风和非黑素瘤皮肤癌共病情况的观察性研究，以及所观察到的关联的可能性及其临床后果。
