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皮肤病学中的营养临床研究。

Nutritional clinical studies in dermatology.

作者信息

Liakou Aikaterini I, Theodorakis Michael J, Melnik Bodo C, Pappas Apostolos, Zouboulis Christos C

出版信息

J Drugs Dermatol. 2013 Oct;12(10):1104-9.

PMID:24085045
Abstract

BACKGROUND & AIMS: Nutrition has long been associated with skin health, beauty, integrity and aging through multiple pathways and cofactors implicated in skin biology. The onset and clinical course of various common skin diseases, especially acne, psoriasis, atopic dermatitis, and hair loss, have been suggested to be critically affected by nutrition patterns and habits. The relationship between acne and diet, predominantly the role of high glycemic load diets and dairy consumption have recently gained increased interest. Abnormal nutritional conditions such as obesity or malnutrition often manifest themselves by specific cutaneous features and altered skin function. Skin photoprotection, rendered by various nutrients, is well documented and appropriate nutritional supplementation has been shown to exert beneficial effects upon impaired skin integrity, restore its appearance and promote skin health. It is our intention to provide a comprehensive review of the most recent information on the role of nutrition for common skin diseases and regulation of skin biology.

METHODS

Nutritional clinical studies in dermatology have been reviewed using the MedLine literature source and the terms "diet" or "nutrition" and "skin".

RESULTS & CONCLUSIONS: The data on the relationship between nutrition and skin are until now controversial and much more work is needed to be done to clarify possible etiological correlations.

摘要

背景与目的

长期以来,营养通过多种参与皮肤生物学过程的途径和辅助因子,与皮肤健康、美观、完整性及衰老相关联。各种常见皮肤病的发病及临床过程,尤其是痤疮、银屑病、特应性皮炎和脱发,被认为受到营养模式和习惯的严重影响。痤疮与饮食之间的关系,主要是高糖负荷饮食和乳制品摄入的作用,最近受到了越来越多的关注。肥胖或营养不良等异常营养状况常通过特定的皮肤特征和皮肤功能改变表现出来。多种营养素提供的皮肤光保护作用已有充分记载,适当的营养补充已被证明对受损的皮肤完整性有有益影响,可恢复其外观并促进皮肤健康。我们旨在全面综述有关营养在常见皮肤病中的作用及皮肤生物学调节方面的最新信息。

方法

使用医学在线文献数据库(MedLine)以及关键词“饮食”或“营养”和“皮肤”,对皮肤病学领域的营养临床研究进行了综述。

结果与结论

到目前为止,关于营养与皮肤之间关系的数据存在争议,需要开展更多工作来阐明可能的病因学关联。

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