朊病毒重塑酵母中的基因表达。
Prions remodel gene expression in yeast.
作者信息
Tuite Mick F, Cox Brian S
机构信息
Kent Fungal Group, Department of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK.
出版信息
Nat Cell Biol. 2009 Mar;11(3):241-3. doi: 10.1038/ncb0309-241.
PMID:19255570
Abstract
Epigenetic mechanisms participate in the regulation of gene transcription in eukaryotes. Two studies in yeast have revealed an additional mechanism for controlling global gene transcription that is based on an inherited self-perpetuating change in the conformation of two different components of key transcriptional regulatory complexes.
摘要
表观遗传机制参与真核生物基因转录的调控。两项针对酵母的研究揭示了一种控制全局基因转录的额外机制，该机制基于关键转录调节复合物的两种不同组分构象的遗传性自我延续变化。
Zotero 插件