多中心联盟中不同种族群体复杂胃食管反流病和巴雷特食管的患病率
Prevalence of complicated gastroesophageal reflux disease and Barrett's esophagus among racial groups in a multi-center consortium.
作者信息
Wang Amy, Mattek Nora C, Holub Jennifer L, Lieberman David A, Eisen Glenn M
机构信息
Department of Gastroenterology, Oregon Health and Science University, 3303 SW Bond Avenue, CHH6D, Portland, OR 97239, USA.
出版信息
Dig Dis Sci. 2009 May;54(5):964-71. doi: 10.1007/s10620-009-0742-3. Epub 2009 Mar 3.
AIMS
The Clinical Outcomes Research Initiative database was used to evaluate ethnic trends in complicated reflux disease and suspected Barrett's esophagus among various racial groups.
METHODS
Endoscopic findings for procedures performed January 2000-December 2005 for any indication and for reflux-related indications were reviewed by racial group.
RESULTS
Of 280,075 procedures examined, Hispanics were the most likely to have esophagitis (Hispanic 19.6%, white 17.3%, black 15.8%, Asian/Pacific Islander 9.5%, P-value<0.0001), and white subjects were most likely to have suspected BE (white 5.0%, Hispanic 2.9%, Asian/Pacific Islander 1.8%, black 1.5%, P-value<0.0001). Endoscopies performed for reflux-related indications had similar trends for esophagitis and esophageal stricture. Among reflux/Barrett's screening procedures adjusted for age and gender, Hispanics were most likely to have esophagitis (OR=1.28, P-value<0.0001) compared to Caucasians.
CONCLUSION
Our results demonstrate an association of suspected Barrett's esophagus and stricture with white patients and esophagitis with Hispanic patients. These findings need to be followed-up with further study.
目的
利用临床结局研究计划数据库评估不同种族群体中复杂性反流性疾病和疑似巴雷特食管的种族趋势。
方法
按种族对2000年1月至2005年12月因任何适应症以及与反流相关适应症进行的内镜检查结果进行回顾。
结果
在280,075例检查的手术中，西班牙裔最易患食管炎（西班牙裔19.6%，白人17.3%，黑人15.8%，亚太岛民9.5%，P值<0.0001），白人受试者最易患疑似巴雷特食管（白人5.0%，西班牙裔2.9%，亚太岛民1.8%，黑人1.5%，P值<0.0001）。因与反流相关适应症进行的内镜检查在食管炎和食管狭窄方面有类似趋势。在按年龄和性别调整的反流/巴雷特筛查手术中，与白种人相比，西班牙裔最易患食管炎（OR = 1.28，P值<0.0001）。
结论
我们的结果表明，疑似巴雷特食管和狭窄与白人患者相关，食管炎与西班牙裔患者相关。这些发现需要进一步研究随访。
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