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Role of the osteoblast lineage in the bone marrow hematopoietic niches.

作者信息

Wu Joy Y, Scadden David T, Kronenberg Henry M

机构信息

Endocrine Unit, Boston, Massachusetts, USA.

出版信息

J Bone Miner Res. 2009 May;24(5):759-64. doi: 10.1359/jbmr.090225.

DOI:10.1359/jbmr.090225
PMID:19257832
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3276348/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94fb/3276348/1977016c28f4/jbmr0024-0759-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94fb/3276348/1977016c28f4/jbmr0024-0759-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94fb/3276348/1977016c28f4/jbmr0024-0759-f1.jpg

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Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair.造血干细胞在稳态和修复过程中从休眠状态可逆地转变为自我更新状态。
Cell. 2008 Dec 12;135(6):1118-29. doi: 10.1016/j.cell.2008.10.048.
2
Detection of functional haematopoietic stem cell niche using real-time imaging.利用实时成像技术检测功能性造血干细胞龛位。
Nature. 2009 Jan 1;457(7225):97-101. doi: 10.1038/nature07639. Epub 2008 Dec 3.
3
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.在其微环境中对单个造血干/祖细胞进行活体动物追踪。
衰老相关血液系统恶性肿瘤中表观遗传学和造血干细胞归巢的新认识。
Stem Cell Res Ther. 2024 Nov 6;15(1):401. doi: 10.1186/s13287-024-04008-4.
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Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone.在纤维化骨的小鼠模型中,使用刺猬抑制剂LGK974抑制Wnt信号通路可减少小梁骨,但不会减少纤维化。
JBMR Plus. 2024 Jan 21;8(5):ziae011. doi: 10.1093/jbmrpl/ziae011. eCollection 2024 May.
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How mesenchymal stem cell cotransplantation with hematopoietic stem cells can improve engraftment in animal models.间充质干细胞与造血干细胞共移植如何改善动物模型中的植入情况。
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