Beernaert L A, Pasmans F, Van Waeyenberghe L, Dorrestein G M, Verstappen F, Vercammen F, Haesebrouck F, Martel A
Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.
Antimicrob Agents Chemother. 2009 May;53(5):2199-201. doi: 10.1128/AAC.01492-08. Epub 2009 Mar 2.
The in vitro susceptibilities of 59 avian Aspergillus fumigatus strains to amphotericin B, itraconazole, and voriconazole were determined using the standard microdilution broth method (CLSI M38-A2). Four isolates showed acquired resistance to itraconazole and voriconazole, harboring implications for the treatment of aspergillosis in both birds and humans.
采用标准微量稀释肉汤法(CLSI M38 - A2)测定了59株禽烟曲霉对两性霉素B、伊曲康唑和伏立康唑的体外敏感性。4株分离株对伊曲康唑和伏立康唑表现出获得性耐药,这对鸟类和人类曲霉病的治疗都有影响。