Nwosu Michelle E, Golomb Meredith R
Division of Pediatric Neurology, Department of Neurology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
J Child Neurol. 2009 Mar;24(3):349-53. doi: 10.1177/0883073808322664.
This report describes a 5-week-old female infant who presented with accidental ingestion of rubbing alcohol (which contains about 70% isopropanol), and was subsequently diagnosed with cerebral sinovenous thrombosis. Isopropanol is a clear, volatile 3-carbon alcohol found in varying concentrations in many solvents. Mislabeled rubbing alcohol was mixed with this patient's formula. After ingesting it, she presented with a 1-day history of uncontrolled fussiness and an episode of deviation of the eyes to the right for 30 minutes, followed by rhythmic movements of the arms and legs for 20 minutes. Cerebral imaging demonstrated sinovenous thrombosis. To our knowledge, there have been no reports describing cerebral sinovenous thrombosis as a complication of isopropanol ingestion. The possible association of isopropanol ingestion and sinovenous thrombosis is discussed.
本报告描述了一名5周大的女婴，她因意外摄入外用酒精（含约70%异丙醇）而就诊，随后被诊断为脑静脉窦血栓形成。异丙醇是一种清澈、易挥发的三碳醇，在许多溶剂中浓度各异。误标为外用酒精的产品与该患者的配方奶混合。摄入后，她出现了1天无法控制的烦躁不安，以及一次右眼偏斜30分钟，随后四肢有节律地运动20分钟的情况。脑部影像学检查显示为静脉窦血栓形成。据我们所知，尚无将脑静脉窦血栓形成描述为异丙醇摄入并发症的报告。本文讨论了异丙醇摄入与静脉窦血栓形成之间可能存在的关联。
