Teitler Joan B
Department of Radiological and Surgical Sciences, University of California-Davis, 95616, USA.
J Am Anim Hosp Assoc. 2009 Mar-Apr;45(2):59-66. doi: 10.5326/0450059.
A rapid, human on-site urine multidrug test was used to screen canine urine samples for the presence of five illegal drugs and drugs from three commonly abused drug classes. Each sample was sent to a toxicology laboratory for gas chromatography/mass spectrometry (GC/MS) validation. On-site test results and GC/MS assays confirmed that the human on-site test kit did identify barbiturates, opiates, benzodiazepines, and amphetamines/methamphetamines in urine from dogs that had received these common illicit drugs/drug classes either intravenously and/or orally. However, neither the on-site test kit nor the GC/MS individual assays for marijuana or methadone, a synthetic opiate, were effective in identifying marijuana and methadone in urine from dogs with suspected or known exposure. No index of suspicion was seen for exposure to phencyclidines or cocaine during the study period, and no exposures were indicated by the on-site test results. Overall, the test is a rapid, readily available, affordable, and useful complement to the veterinarian's clinical consideration and professional judgment.
使用一种快速的现场人体尿液多药物检测方法，对犬类尿液样本进行筛查，以检测五种非法药物以及来自三种常见滥用药物类别的药物。每个样本都被送往毒理学实验室进行气相色谱/质谱（GC/MS）验证。现场检测结果和GC/MS分析证实，该人体现场检测试剂盒确实能在静脉内和/或口服过这些常见非法药物/药物类别的犬类尿液中识别出巴比妥类药物、阿片类药物、苯二氮卓类药物以及苯丙胺/甲基苯丙胺。然而，无论是现场检测试剂盒还是针对大麻或美沙酮（一种合成阿片类药物）的GC/MS单独检测，都无法有效识别疑似或已知接触过大麻和美沙酮的犬类尿液中的大麻和美沙酮。在研究期间，未发现有苯环己哌啶或可卡因接触的可疑迹象，现场检测结果也未显示有此类接触。总体而言，该检测是对兽医临床考虑和专业判断的一种快速、易于获取、经济实惠且有用的补充。
