Woese Carl R, Goldenfeld Nigel
Institute for Genomic Biology and Department of Physics, 1206 West Gregory Drive, Urbana, IL 61801, USA.
Microbiol Mol Biol Rev. 2009 Mar;73(1):14-21. doi: 10.1128/MMBR.00002-09.
In this commentary, we provide a personal overview of the conceptual history of microbiology and molecular biology over the course of the last hundred years, emphasizing the relationship of these fields to the problem of evolution. We argue that despite their apparent success, all three reached an impasse that arose from the influence of dogmatic or overly narrow perspectives. Finally, we describe how recent developments in microbiology are realizing Beijerinck's vision of a field that is fully integrated with molecular biology, microbial ecology, thereby challenging and extending current thinking in evolution.
在这篇评论中，我们对过去百年间微生物学和分子生物学的概念史进行了个人视角的概述，着重阐述了这些领域与进化问题的关系。我们认为，尽管这三个领域表面上取得了成功，但都因教条主义或过于狭隘的观点影响而陷入了僵局。最后，我们描述了微生物学的最新进展如何正在实现贝杰林克所设想的一个与分子生物学、微生物生态学完全融合的领域，从而挑战并拓展了当前进化领域的思维。
