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“防火带”全厚皮片移植能否预防Dupuytren挛缩症手术后的复发?一项前瞻性随机试验。

Does a 'firebreak' full-thickness skin graft prevent recurrence after surgery for Dupuytren's contracture?: a prospective, randomised trial.

作者信息

Ullah A S, Dias J J, Bhowal B

机构信息

Department of Orthopaedic Surgery, University Hospitals of Leicester NHS Trust, Groby Road, Leicester LE3 9QP, UK.

出版信息

J Bone Joint Surg Br. 2009 Mar;91(3):374-8. doi: 10.1302/0301-620X.91B3.21054.

Abstract

We randomised 79 patients (84 hands, 90 fingers) with Dupuytren's contracture of the proximal interphalangeal joint to have either a 'firebreak' skin graft (39 patients, 41 hands, 44 fingers) or a fasciectomy (40 patients, 43 hands, 46 fingers) if, after full correction, the skin over the proximal phalanx could be easily closed by a Z-plasty. Patients were reviewed after three, six, 12, 24 and 36 months to note any complications, the range of movement and recurrence. Both groups were similar in regard to age, gender and factors considered to influence the outcome such as bilateral disease, family history, the presence of diabetes, smoking and alcohol intake. The degree of contracture of the metacarpophalangeal and interphalangeal joints of the operated fingers was similar in the two groups and both were comparable in terms of grip strength, range of movement and disability at each follow-up. The recurrence rate was 12.2%. We did not identify any improvement in correction or recurrence of contracture after firebreak dermofasciectomy up to three years after surgery.

摘要

我们将79例近端指间关节掌腱膜挛缩患者(84只手,90根手指)随机分组,若近端指骨上的皮肤在完全矫正后可通过Z成形术轻松闭合,则其中39例患者(41只手,44根手指)接受“防火带”皮肤移植,40例患者(43只手,46根手指)接受筋膜切除术。在术后3个月、6个月、12个月、24个月和36个月对患者进行复查,记录任何并发症、活动范围和复发情况。两组患者在年龄、性别以及被认为会影响结果的因素(如双侧疾病、家族史、糖尿病的存在、吸烟和饮酒情况)方面相似。两组中手术手指的掌指关节和指间关节挛缩程度相似,在每次随访时,两组在握力、活动范围和残疾程度方面也具有可比性。复发率为12.2%。在术后长达三年的时间里,我们未发现“防火带”真皮筋膜切除术后在挛缩矫正或复发方面有任何改善。

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