Brolin R E, Flancbaum L, Ercoli F R, Milgrim L M, Bocage J P, Blum A, Needell G S, Nosher J L
Department of Surgery, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick 08903-0019.
Surg Gynecol Obstet. 1991 Sep;173(3):203-10.
During the past eight years, 119 patients with abdominal abscesses underwent percutaneous catheter drainage (PCD), including 76 who had successful treatment by the initial PCD, 19 who had recurrent abscesses after removal of drainage catheters and 24 who were outright failures and either died of sepsis or required surgical drainage. This study was designed to identify outcome variables that might be used prospectively to assess the therapeutic efficacy of PCD. Outcome variables included abscess size, daily drainage volume and location, presence of a gastrointestinal fistula, age, bacteriologic factors and response of the pulse rate, body temperature and leukocyte count of the patient to PCD. Ninety of 119 patients (76 per cent) ultimately had successful drainage of abscesses by PCD alone. The over-all mortality rate was 16 per cent (19 of 119), with a 75 per cent mortality rate in the failure group. Neither abscess size, bacteriologic findings nor pulse rate correlated with outcome. PCD failure was significantly greater in patients greater than or equal to 60 years (p less than or equal to 0.01) and in patients with pancreatic abscesses versus other locations (p less than or equal to 0.04). Drainage volume was significantly greater in PCD failures than among PCD successes at greater than or equal to 3 days after PCD (p less than or equal to 0.03).(ABSTRACT TRUNCATED AT 250 WORDS)
在过去八年中,119例腹部脓肿患者接受了经皮导管引流(PCD)治疗,其中76例通过初始PCD获得成功治疗,19例在拔除引流导管后出现复发性脓肿,24例彻底治疗失败,要么死于败血症,要么需要手术引流。本研究旨在确定可能用于前瞻性评估PCD治疗效果的预后变量。预后变量包括脓肿大小、每日引流量及位置、胃肠道瘘的存在、年龄、细菌学因素以及患者的脉搏率、体温和白细胞计数对PCD的反应。119例患者中有90例(76%)最终仅通过PCD成功引流了脓肿。总体死亡率为16%(119例中的19例),失败组的死亡率为75%。脓肿大小、细菌学检查结果和脉搏率均与预后无关。年龄大于或等于60岁的患者以及胰腺脓肿患者与其他部位脓肿患者相比,PCD失败率显著更高(p≤0.01和p≤0.04)。PCD失败患者在PCD后大于或等于3天的引流量显著高于PCD成功患者(p≤0.03)。(摘要截短至250字)