通过三维傅里叶域光学相干断层扫描比较视网膜疾病中反射率图与视网膜外层地形图。
Comparison of reflectivity maps and outer retinal topography in retinal disease by 3-D Fourier domain optical coherence tomography.
作者信息
Wojtkowski Maciej, Sikorski Bartosz L, Gorczynska Iwona, Gora Michalina, Szkulmowski Maciej, Bukowska Danuta, Kaluzny Jakub, Fujimoto James G, Kowalczyk Andrzej
机构信息
Institute of Physics, Nicolaus Copernicus University, Grudziadzka 5/7, PL-87-100 Toruń, Poland.
出版信息
Opt Express. 2009 Mar 2;17(5):4189-207. doi: 10.1364/oe.17.004189.
Abstract
We demonstrate and compare two image processing methods for visualization and analysis of three-dimensional optical coherence tomography (OCT) data acquired in eyes with different retinal pathologies. A method of retinal layer segmentation based on a multiple intensity thresholding algorithm was implemented in order to generate simultaneously outer retinal topography maps and reflectivity maps. We compare the applicability of the two methods to the diagnosis of retinal diseases and their progression. The data presented in this contribution were acquired with a high speed (25,000 A-scans/s), high resolution (4.5 microm) spectral OCT prototype instrument operating in the ophthalmology clinic.
摘要
我们展示并比较了两种图像处理方法，用于可视化和分析在患有不同视网膜病变的眼睛中获取的三维光学相干断层扫描（OCT）数据。为了同时生成视网膜外层地形图和反射率图，实施了一种基于多强度阈值算法的视网膜层分割方法。我们比较了这两种方法在视网膜疾病诊断及其进展方面的适用性。本论文中呈现的数据是使用一台在眼科诊所运行的高速（25,000次A扫描/秒）、高分辨率（4.5微米）光谱OCT原型仪器采集的。
相似文献
1
Comparison of reflectivity maps and outer retinal topography in retinal disease by 3-D Fourier domain optical coherence tomography.通过三维傅里叶域光学相干断层扫描比较视网膜疾病中反射率图与视网膜外层地形图。
Opt Express. 2009 Mar 2;17(5):4189-207. doi: 10.1364/oe.17.004189.
2
Three-dimensional ultrahigh resolution optical coherence tomography imaging of age-related macular degeneration.年龄相关性黄斑变性的三维超高分辨率光学相干断层扫描成像
Opt Express. 2009 Mar 2;17(5):4046-60. doi: 10.1364/oe.17.004046.
3
Retinal imaging by spectral optical coherence tomography.通过光谱光学相干断层扫描进行视网膜成像。
Eur J Ophthalmol. 2007 Mar-Apr;17(2):238-45. doi: 10.1177/112067210701700214.
4
High-definition and 3-dimensional imaging of macular pathologies with high-speed ultrahigh-resolution optical coherence tomography.利用高速超高分辨率光学相干断层扫描技术对黄斑病变进行高清三维成像。
Ophthalmology. 2006 Nov;113(11):2054.e1-14. doi: 10.1016/j.ophtha.2006.05.046.
5
Choroid, Haller's, and Sattler's layer thickness in intermediate age-related macular degeneration with and without fellow neovascular eyes.伴有和不伴有对侧新生血管性眼的中年年龄相关性黄斑变性中脉络膜、哈勒层和萨特勒层的厚度
Invest Ophthalmol Vis Sci. 2014 Jul 22;55(8):5074-80. doi: 10.1167/iovs.14-14646.
6
Ultrahigh-resolution versus speckle noise-reduction in spectral-domain optical coherence tomography.光谱域光学相干断层扫描中的超高分辨率与散斑噪声降低
Opt Express. 2009 Mar 2;17(5):4221-35. doi: 10.1364/oe.17.004221.
7
Three-dimensional retinal imaging with high-speed ultrahigh-resolution optical coherence tomography.采用高速超高分辨率光学相干断层扫描技术的三维视网膜成像
Ophthalmology. 2005 Oct;112(10):1734-46. doi: 10.1016/j.ophtha.2005.05.023.
8
Analysis of the outer retina reconstructed by high-resolution, three-dimensional spectral domain optical coherence tomography.
Ophthalmic Surg Lasers Imaging. 2009 Mar-Apr;40(2):102-8. doi: 10.3928/15428877-20090301-10.
9
Optical coherence tomography of age-related macular degeneration and choroidal neovascularization.年龄相关性黄斑变性和脉络膜新生血管的光学相干断层扫描
Ophthalmology. 1996 Aug;103(8):1260-70. doi: 10.1016/s0161-6420(96)30512-5.
10
Comparison of ultrahigh- and standard-resolution optical coherence tomography for imaging macular pathology.超高分辨率与标准分辨率光学相干断层扫描成像黄斑病变的比较。
Ophthalmology. 2005 Nov;112(11):1922.e1-15. doi: 10.1016/j.ophtha.2005.05.027. Epub 2005 Sep 23.
引用本文的文献
1
Crosstalk-free volumetric imaging of a human retina with Fourier-domain full-field optical coherence tomography.基于傅里叶域全场光学相干断层扫描技术的人体视网膜无串扰容积成像
Biomed Opt Express. 2019 Nov 20;10(12):6390-6407. doi: 10.1364/BOE.10.006390. eCollection 2019 Dec 1.
2
Association between Visual Acuity and Retinal Layer Metrics in Diabetics with and without Macular Edema.伴有和不伴有黄斑水肿的糖尿病患者视力与视网膜层指标之间的关联
J Ophthalmol. 2018 Oct 3;2018:1089043. doi: 10.1155/2018/1089043. eCollection 2018.
3
Optical coherence tomography (OCT) with 2 nm axial resolution using a compact laser plasma soft X-ray source.采用紧凑型激光等离子体软 X 射线源实现轴向分辨率为 2nm 的光学相干断层扫描（OCT）。
Sci Rep. 2018 May 31;8(1):8494. doi: 10.1038/s41598-018-26909-0.
4
Twenty-five years of optical coherence tomography: the paradigm shift in sensitivity and speed provided by Fourier domain OCT [Invited].光学相干断层扫描的二十五年：傅里叶域光学相干断层扫描带来的灵敏度和速度的范式转变[特邀报告]
Biomed Opt Express. 2017 Jun 15;8(7):3248-3280. doi: 10.1364/BOE.8.003248. eCollection 2017 Jul 1.
5
Enhanced Visualization of Subtle Outer Retinal Pathology by En Face Optical Coherence Tomography and Correlation with Multi-Modal Imaging.通过表面光学相干断层扫描增强对视网膜外层细微病变的可视化及其与多模态成像的相关性
PLoS One. 2016 Dec 13;11(12):e0168275. doi: 10.1371/journal.pone.0168275. eCollection 2016.
6
OCT angiography by absolute intensity difference applied to normal and diseased human retinas.通过绝对强度差异进行的光学相干断层扫描血管造影术应用于正常和患病的人类视网膜。
Biomed Opt Express. 2015 Jul 6;6(8):2738-54. doi: 10.1364/BOE.6.002738. eCollection 2015 Aug 1.
7
ASSESSING PHOTORECEPTOR STRUCTURE ASSOCIATED WITH ELLIPSOID ZONE DISRUPTIONS VISUALIZED WITH OPTICAL COHERENCE TOMOGRAPHY.评估与光学相干断层扫描显示的椭圆体区破坏相关的光感受器结构。
Retina. 2016 Jan;36(1):91-103. doi: 10.1097/IAE.0000000000000618.
8
Identification of Drusen Characteristics in Age-Related Macular Degeneration by Polarization-Sensitive Optical Coherence Tomography.通过偏振敏感光学相干断层扫描识别年龄相关性黄斑变性中的玻璃膜疣特征
Am J Ophthalmol. 2015 Aug;160(2):335-344.e1. doi: 10.1016/j.ajo.2015.05.008. Epub 2015 May 15.
9
A Method for En Face OCT Imaging of Subretinal Fluid in Age-Related Macular Degeneration.一种用于年龄相关性黄斑变性中视网膜下液的正面光学相干断层扫描成像方法。
J Ophthalmol. 2014;2014:720243. doi: 10.1155/2014/720243. Epub 2014 Oct 13.
10
Quantitative analysis of retinal layer optical intensities on three-dimensional optical coherence tomography.三维光学相干断层扫描中视网膜层光强度的定量分析。
Invest Ophthalmol Vis Sci. 2013 Oct 21;54(10):6846-51. doi: 10.1167/iovs.13-12062.
本文引用的文献
1
Transversal and longitudinal images from the retina of the living eye using low coherence reflectometry.使用低相干反射测量法获取的活体眼睛视网膜的横向和纵向图像。
J Biomed Opt. 1998 Jan;3(1):12-20. doi: 10.1117/1.429859.
2
Simultaneous acquisition of sectional and fundus ophthalmic images with spectral-domain optical coherence tomography.利用光谱域光学相干断层扫描技术同时采集眼部断层图像和眼底图像。
Opt Express. 2005 Jan 24;13(2):444-52. doi: 10.1364/opex.13.000444.
3
Ultrahigh-resolution high-speed retinal imaging using spectral-domain optical coherence tomography.使用谱域光学相干断层扫描的超高分辨率高速视网膜成像。
Opt Express. 2004 May 31;12(11):2435-47. doi: 10.1364/opex.12.002435.
4
Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation.超高分辨率、高速傅里叶域光学相干断层扫描及色散补偿方法。
Opt Express. 2004 May 31;12(11):2404-22. doi: 10.1364/opex.12.002404.
5
Ultrahigh resolution Fourier domain optical coherence tomography.超高分辨率傅里叶域光学相干断层扫描术
Opt Express. 2004 May 17;12(10):2156-65. doi: 10.1364/opex.12.002156.
6
Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography.通过彩色多普勒傅里叶域光学相干断层扫描进行超快速采集对视网膜血流进行实时评估。
Opt Express. 2003 Nov 17;11(23):3116-21. doi: 10.1364/oe.11.003116.
7
Three-dimensional imaging of the human retina by high-speed optical coherence tomography.利用高速光学相干断层扫描技术对人视网膜进行三维成像。
Opt Express. 2003 Oct 20;11(21):2753-61. doi: 10.1364/oe.11.002753.
8
Three dimensional OCT images from retina and skin.来自视网膜和皮肤的三维光学相干断层扫描图像。
Opt Express. 2000 Oct 23;7(9):292-8. doi: 10.1364/oe.7.000292.
9
Analysis of the outer retina reconstructed by high-resolution, three-dimensional spectral domain optical coherence tomography.
Ophthalmic Surg Lasers Imaging. 2009 Mar-Apr;40(2):102-8. doi: 10.3928/15428877-20090301-10.
10
Projection OCT fundus imaging for visualising outer retinal pathology in non-exudative age-related macular degeneration.用于可视化非渗出性年龄相关性黄斑变性中视网膜外层病变的投影光学相干断层扫描眼底成像
Br J Ophthalmol. 2009 May;93(5):603-9. doi: 10.1136/bjo.2007.136101. Epub 2008 Jul 28.
Zotero 插件