Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA.
Int J Eat Disord. 2010 Jan;43(1):14-21. doi: 10.1002/eat.20670.
We examined prevalence of substance use disorders (SUD) in women with: (1) anorexia nervosa (AN) restricting type (RAN); (2) AN with purging only (PAN); (3) AN with binge eating only (BAN); and (4) lifetime AN and bulimia nervosa (ANBN). Secondary analyses examined SUD related to lifetime purging behavior and lifetime binge eating.
Participants (N = 731) were drawn from the International Price Foundation Genetic Studies.
The prevalence of SUD differed across AN subtypes, with more in the ANBN group reporting SUD than those in the RAN and PAN groups. Individuals who purged were more likely to report substance use than those who did not purge. Prevalence of SUD differed across lifetime binge eating status.
SUD are common in AN and are associated with bulimic symptomatology. Results underscore the heterogeneity in AN, highlighting the importance of screening for SUD across AN subtypes.
我们研究了以下女性的物质使用障碍(SUD)患病率:(1)神经性厌食症(AN)限制型(RAN);(2)仅暴食型(PAN);(3)仅贪食型(BAN);以及(4)终生 AN 和神经性贪食症(ANBN)。次要分析检查了与终生暴食行为和终生贪食相关的 SUD。
参与者(N=731)来自国际价格基金会遗传研究。
SUD 的患病率因 AN 亚型而异,ANBN 组报告 SUD 的人数多于 RAN 和 PAN 组。有过暴食行为的人比没有暴食行为的人更有可能报告物质使用。SUD 的患病率因终生暴食状态而异。
SUD 在 AN 中很常见,与贪食症状有关。结果突出了 AN 的异质性,强调了在 AN 亚型中筛查 SUD 的重要性。