Corvera-Tindel Teresita, Doering Lynn V, Roper Janice, Dracup Kathleen
VA Nursing Research Department, VA Greater Los Angeles Health Care System, School of Nursing, University of California, Los Angeles, CA 90073, USA.
Prog Cardiovasc Nurs. 2009 Mar;24(1):2-11. doi: 10.1111/j.1751-7117.2009.00026.x.
The purpose of this study was to examine the relative contributions of physical and emotional functioning to overall quality of life (QOL) in men with heart failure (HF). In 76 men with HF (age 63+/-11 years; left ventricular ejection fraction 27+/-9%; 20% NYHA III/IV), initial correlations of Cardiac-Quality of Life Index (C-QLI) scores with sociodemographic/clinical variables, physical functioning (6-minute walk test and Heart Failure Functional Status Inventory), and emotional functioning (depression, anxiety, and hostility, as measured by the Multiple Affect Adjective Checklist) were followed by multivariate stepwise regression. After controlling for sociodemographic/clinical variables, younger age (variance=9%, P=.008), higher depressive symptoms (variance=16%, P=or<.001), and lower self-reported physical functioning (variance=4%, P=.03) accounted for lower C-QLI scores (R2=0.33, P=.03). Compared with physical functioning, emotional functioning and younger age have a stronger relationship to QOL in men with HF.
本研究旨在探讨身体功能和情绪功能对心力衰竭(HF)男性患者总体生活质量(QOL)的相对贡献。对76例HF男性患者(年龄63±11岁;左心室射血分数27±9%;20%为纽约心脏协会III/IV级),首先分析心脏生活质量指数(C-QLI)得分与社会人口统计学/临床变量、身体功能(6分钟步行试验和心力衰竭功能状态量表)以及情绪功能(通过多重情感形容词检查表测量的抑郁、焦虑和敌意)之间的初始相关性,然后进行多变量逐步回归分析。在控制社会人口统计学/临床变量后,年龄较小(方差=9%,P=0.008)、抑郁症状较重(方差=16%,P≤0.001)以及自我报告的身体功能较差(方差=4%,P=0.03)导致C-QLI得分较低(R2=0.33,P=0.03)。与身体功能相比,情绪功能和年龄较小与HF男性患者的生活质量关系更强。