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采用布鲁克回肠造口术的微创全直肠结肠切除术治疗溃疡性结肠炎。

Minimally invasive total proctocolectomy with Brooke ileostomy for ulcerative colitis.

作者信息

Holubar Stefan D, Privitera Antonio, Cima Robert R, Dozois Eric J, Pemberton John H, Larson David W

机构信息

Division of Colon and Rectal Surgery, Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA.

出版信息

Inflamm Bowel Dis. 2009 Sep;15(9):1337-42. doi: 10.1002/ibd.20914.

Abstract

BACKGROUND

Total proctocolectomy with Brooke ileostomy remains the optimal surgical procedure for select ulcerative colitis patients. However, few studies describe outcomes of minimally invasive total proctocolectomy with Brooke ileostomy. Our aim was to describe the safety and feasibility of these procedures by examining short-term (30-day) outcomes.

METHODS

Using a prospective database, we identified a cohort of patients who underwent laparoscopic total proctocolectomy with Brooke ileostomy at our institution from 2000-2007. Results are reported as median (range) or frequency (proportion).

RESULTS

Forty-four patients were included; age 65 years (54-73), 24 were male (55%), body mass index was 26.5 (22.1-30.2) kg/m(2). Colitis duration was 66 months (24-240), and 40% had prior surgery. The indication for surgery was refractory colitis (82%) and neoplasia (18%). Factors influencing choice of total proctocolectomy with permanent ileostomy were advanced age in 18 (41%), lifestyle in 13 (30%), medical comorbidities in 11 (25%), fecal incontinence in 10 (23%), oncologic reasons in 3 (6.8%), and obesity in 3 (6.8%). Twenty-three (52%) operations were hand-assisted laparoscopic surgery, 13 (30%) were laparoscopic-assisted, and 8 (18%) were "laparoscopic-incisionless" with transanal specimen extraction. Two laparoscopic-assisted cases (4.6%) were converted. Operative time was 329 (272-402) minutes, and length of stay 5 (4-6) days. Major post-operative complications occurred in 4 (9%); there were no perioperative mortalities.

CONCLUSIONS

Minimally invasive total proctocolectomy with Brooke ileostomy is a safe, feasible option for the surgical treatment of chronic ulcerative colitis, and is the procedure of choice for select patients.

摘要

背景

对于部分溃疡性结肠炎患者,行布鲁克回肠造口术的全直肠结肠切除术仍是最佳手术方式。然而,很少有研究描述行布鲁克回肠造口术的微创全直肠结肠切除术的结果。我们的目的是通过检查短期(30天)结果来描述这些手术的安全性和可行性。

方法

利用前瞻性数据库,我们确定了2000年至2007年在本机构接受腹腔镜全直肠结肠切除术并做布鲁克回肠造口术的一组患者。结果以中位数(范围)或频率(比例)报告。

结果

纳入44例患者;年龄65岁(54 - 73岁),男性24例(55%),体重指数为26.5(22.1 - 30.2)kg/m²。结肠炎病程为66个月(24 - 240个月),40%的患者曾接受过手术。手术指征为难治性结肠炎(82%)和肿瘤(18%)。影响选择永久性回肠造口的全直肠结肠切除术的因素包括高龄(18例,41%)、生活方式(13例,30%)、内科合并症(11例,25%)、大便失禁(10例,23%)、肿瘤学原因(3例,6.8%)和肥胖(3例,6.8%)。23例(52%)手术为手辅助腹腔镜手术,13例(30%)为腹腔镜辅助手术,8例(18%)为经肛门标本取出的“腹腔镜无切口”手术。2例腹腔镜辅助病例(4.6%)中转开腹。手术时间为329(272 - 402)分钟,住院时间为5(4 - 6)天。主要术后并发症发生4例(9%);无围手术期死亡病例。

结论

行布鲁克回肠造口术的微创全直肠结肠切除术是慢性溃疡性结肠炎外科治疗的一种安全、可行的选择,也是部分患者的首选术式。

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