Novikov Vadim V, Novikov Gleb V, Fesenko Evgeny E
Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia.
Bioelectromagnetics. 2009 Jul;30(5):343-51. doi: 10.1002/bem.20487.
It has been shown that the ultralow-frequency extremely weak alternating component of combined magnetic fields (MFs) exhibits a marked antitumor activity. The parameters of this component have been found (frequency 1, 4.4, 16.5 Hz or the sum of these frequencies; intensity 300, 100, 150-300 nT, respectively) at which this MF in combination with a collinear static MF of 42 microT inhibits or suppresses the growth of Ehrlich ascites carcinoma (EAC) in mice. It was shown that the exposure of mice with EAC to combined MFs causes structural changes in some organs (liver, adrenal glands), which are probably due to the total degradation of the tumor tissue. In mice with transplanted EAC, the tumor tissue after exposure to weak MFs was practically absent, as distinct from control animals in which the invasion of the tumor into the adipose tissue surrounding the kidneys, mesenteric lymph nodes, and spermatic appendages was observed. In animals without tumors, no pathological deviations from the norm in the structure of organs and tissues occurred after exposure to weak MF, indicating that this factor per se is not toxic to the organism.
研究表明，复合磁场的超低频极弱交变分量具有显著的抗肿瘤活性。已发现该分量的参数（频率为1、4.4、16.5 Hz或这些频率之和；强度分别为300、100、150 - 300 nT），在此参数下，该复合磁场与42 μT的共线静磁场相结合，可抑制或抑制小鼠艾氏腹水癌（EAC）的生长。结果表明，EAC小鼠暴露于复合磁场会导致某些器官（肝脏、肾上腺）发生结构变化，这可能是由于肿瘤组织的整体降解所致。在移植了EAC的小鼠中，暴露于弱复合磁场后肿瘤组织几乎消失，这与对照动物不同，在对照动物中观察到肿瘤侵入肾脏周围的脂肪组织、肠系膜淋巴结和精索附件。在无肿瘤的动物中，暴露于弱复合磁场后，器官和组织结构未出现与正常情况的病理偏差，这表明该因素本身对生物体无毒。
