Monderer Renee, Thorpy Michael
Sleep Wake Disorders Center, Montefiore Medical Center, 3411 Wayne Avenue, Bronx, NY 10467, USA.
Curr Neurol Neurosci Rep. 2009 Mar;9(2):173-80. doi: 10.1007/s11910-009-0026-5.
Patients with Parkinson's disease commonly have sleep disturbances that significantly alter quality of life but are often underrecognized. Awareness of the importance of these sleep disorders has been growing, and more research is being conducted. Patients with Parkinson's disease have difficulties that not only include falling asleep and staying asleep but also include excessive daytime sleepiness and abnormal events during sleep. These sleep disturbances are often multifactorial in nature, resulting from degeneration of the cortical sleep centers to effects of medications taken to treat the motor symptoms associated with Parkinson's disease. A thorough evaluation should be performed to assess for the presence of sleep disturbances and daytime sleepiness. Many therapeutic strategies can be used to treat sleepiness and sleep disturbances in Parkinson's disease to improve the patient's overall health, psychological well-being, and quality of life.
帕金森病患者通常存在睡眠障碍，这会显著改变生活质量，但往往未得到充分认识。对这些睡眠障碍重要性的认识一直在提高，并且正在进行更多研究。帕金森病患者存在的困难不仅包括入睡困难和维持睡眠困难，还包括日间过度嗜睡以及睡眠期间的异常事件。这些睡眠障碍通常具有多因素性质，起因于皮质睡眠中枢的退化以及用于治疗与帕金森病相关运动症状的药物的影响。应进行全面评估以确定是否存在睡眠障碍和日间嗜睡。许多治疗策略可用于治疗帕金森病患者的嗜睡和睡眠障碍，以改善患者的整体健康、心理健康和生活质量。
