前路颈椎间盘切除并采用结构性同种异体骨移植及钢板融合术治疗不稳定型颈椎后路损伤。
Anterior cervical discectomy and fusion with structural allograft and plates for the treatment of unstable posterior cervical spine injuries.
作者信息
Woodworth Richard S, Molinari William J, Brandenstein Daniel, Gruhn William, Molinari Robert W
机构信息
Department of Orthopaedics, University of Rochester, New York, USA.
出版信息
J Neurosurg Spine. 2009 Feb;10(2):93-101. doi: 10.3171/2008.11.SPI08615.
OBJECT
The purpose of this study was to evaluate complications and radiographic and functional outcomes of isolated anterior stabilization surgery in which structural allograft and plates were used for posterior unstable subaxial cervical spine lateral mass, facet, and ligamentous injuries.
METHODS
Between August 2003 and January 2008, 19 consecutive patients with unstable lateral mass, facet, and/or posterior ligamentous injuries of the subaxial cervical spine were treated by a single surgeon via an anterior approach. This was performed using structural allograft and plate fixation. Patients with any associated anterior vertebral fractures were excluded from the study. Autogenous bone grafts or bone graft substitutes were not used in any patient. The average age of the patients was 43 years (range 17-87 years) and the mean follow-up period was 20.4 months (range 6-48 months). Seventeen of the 19 patients participated in the study; the other 2 were lost to follow-up. Operative times, estimated blood loss, length of hospital stay (LOS), and perioperative complications were recorded for each patient. Radiographic outcomes included fusion scores and sagittal alignment measurements. Outcome scores with respect to neck pain, satisfaction with surgery, and function were recorded for each patient according to analog pain and satisfaction scales and the Neck Disability Index (NDI). Additionally, NDI and pain scores at final follow-up were compared with a group of healthy, age-matched controls.
RESULTS
The average surgical time was 60 minutes (range 28-108 minutes), and the estimated blood loss averaged 48.9 ml per surgical procedure (range 20-150 ml). The LOS for the 13 patients who had no other associated injuries averaged 2.2 days (range 2-3 days). Fifteen of 17 patients achieved solid radiographic fusion, and no patient demonstrated instability. Only 1 patient had significant loss of the initial sagittal alignment correction at final follow-up. The average NDI score for the 17 patients was 6.5 (range 0-11), indicating mild disability and comparing favorably to a group of healthy age-matched controls. There was no statistical difference in pain scores for the trauma patients and control group at ultimate follow-up (1.5 vs 0.3, respectively). Satisfaction scores for the 17 trauma patients were high, averaging 94% (range 80-100%). Ten of the 11 patients with preoperative radiculopathy demonstrated complete resolution of this condition. Complications occurred in 1 patient with transient hoarseness and 1 with transient swallowing difficulty. There were no wound complications. Screw breakage occurred in 1 patient, and an additional patient required revision surgery for pseudarthrosis.
CONCLUSIONS
Anterior cervical discectomy and fusion performed using interbody structural allograft and plate fixation is highly effective in the treatment of unstable posterior cervical lateral mass, facet, and ligamentous injuries. This treatment option results in low intraoperative blood loss, short operating times, and a brief LOS. Radiographic outcomes with respect to segmental stability are excellent, and fusion rates with the use of structural allograft alone are high. Outcomes with respect to pain, function, and patient satisfaction are high, and complications are acceptably low.
目的
本研究旨在评估采用结构性同种异体骨和钢板治疗下颈椎后部不稳定的侧块、关节突及韧带损伤的单纯前路稳定手术的并发症、影像学及功能结果。
方法
2003年8月至2008年1月,19例下颈椎侧块、关节突及/或后部韧带损伤不稳定的连续患者由同一位外科医生采用前路入路进行治疗。采用结构性同种异体骨和钢板固定。任何伴有前路椎体骨折的患者均被排除在研究之外。所有患者均未使用自体骨移植或骨移植替代物。患者平均年龄43岁(范围17 - 87岁),平均随访期为20.4个月(范围6 - 48个月)。19例患者中有17例参与了研究;另外2例失访。记录每位患者的手术时间、估计失血量、住院时间(LOS)及围手术期并发症。影像学结果包括融合评分和矢状面排列测量。根据视觉模拟疼痛和满意度量表以及颈部功能障碍指数(NDI)记录每位患者关于颈部疼痛、手术满意度及功能的结果评分。此外,将最终随访时的NDI和疼痛评分与一组年龄匹配的健康对照进行比较。
结果
平均手术时间为60分钟(范围28 - 108分钟),每次手术估计失血量平均为48.9 ml(范围20 - 150 ml)。13例无其他相关损伤的患者住院时间平均为2.2天(范围2 - 3天)。17例患者中有15例获得了坚实的影像学融合,无患者出现不稳定。仅1例患者在最终随访时初始矢状面排列矫正有明显丢失。17例患者的平均NDI评分为6.5(范围0 - 11),表明为轻度功能障碍且与一组年龄匹配的健康对照相比情况良好。创伤患者和对照组在最终随访时的疼痛评分无统计学差异(分别为1.5和0.3)。17例创伤患者的满意度评分较高,平均为94%(范围80 - 100%)。11例术前有神经根病的患者中有10例症状完全缓解。并发症发生在1例出现短暂声音嘶哑和1例出现短暂吞咽困难的患者身上。无伤口并发症。1例患者发生螺钉断裂,另1例患者因假关节形成需要翻修手术。
结论
采用椎间结构性同种异体骨和钢板固定进行的颈椎前路椎间盘切除融合术在治疗不稳定的颈椎后部侧块、关节突及韧带损伤方面非常有效。这种治疗方法术中失血量少、手术时间短且住院时间短。关于节段稳定性的影像学结果极佳,仅使用结构性同种异体骨的融合率很高。关于疼痛、功能及患者满意度的结果良好,并发症发生率低且可接受。