Seeman J
J Hyg Epidemiol Microbiol Immunol. 1976;20(4):489-96.
The population from different regions of the CSR was examined serologically for the presence of cytomegalovirus (CMV) antibodies. Exclusively persons showing no signs of disease, chosen by random selection, were examined. The immunological survey was carried out by the complement fixation reaction with CMV antigen prepared in the laboratory from the international strain AD 169. The high incidence found in normal population is suggestive of a considerable dispersion of cytomegalovirus infection. The contact with the virus is followed by antibody response, manifested in most cases only subclinically and asymptomatically. The incidence of CMV antibodies increases with increasing age. In young age groups, antibodies were found in approximately 20%. The number of persons showing positive reactions increased gradually and in the oldest age groups antibodies were found in 70%. The significance of factors causing the incidence of cytomegalovirus antibodies in the population is discussed.
对社区不同地区的人群进行了血清学检查，以检测巨细胞病毒（CMV）抗体的存在。仅对随机挑选的无疾病迹象的人进行了检查。免疫调查采用补体结合反应，使用实验室从国际毒株AD 169制备的CMV抗原进行。正常人群中发现的高发病率表明巨细胞病毒感染有相当大的传播范围。接触该病毒后会产生抗体反应，在大多数情况下仅表现为亚临床和无症状。CMV抗体的发病率随年龄增长而增加。在年轻年龄组中，约20%的人发现有抗体。呈阳性反应的人数逐渐增加，在最年长的年龄组中，70%的人发现有抗体。文中讨论了导致人群中巨细胞病毒抗体发病率的因素的意义。
