槟城的巨细胞病毒感染：一项血清学调查。

Cytomegalovirus infection in Penang: a serological survey.

作者信息

Madhavan H N, Ong K H, Anuar K

出版信息

Southeast Asian J Trop Med Public Health. 1986 Jun;17(2):168-71.

Abstract

During 1984-1985, a total of 838 sera obtained from individuals of different age groups, mostly blood donors and those whose sera were received for VDRL tests and other serological investigations. The sera were titrated for complement fixing antibodies against cytomegalovirus (Ad169 strain). Three hundred and fifty two (41%) out of 838 sera showed significant antibody titre. The incidence of this virus infection varied form 26% in the age group of 11-20 years to 59% of those above 50 years of age. Geometric mean titre (GMT) was highest (22) in age groups of 11-20 years and those over 50 years indicating active viral infection in these two age groups. GMT was also significantly higher in females in all age groups except in the age group of 21-30 years and those above 50 years, indicating that active viral infection is more common in females.

摘要

在1984年至1985年期间，共采集了838份来自不同年龄组个体的血清样本，其中大部分是献血者以及那些因进行性病研究实验室玻片试验（VDRL）检测和其他血清学检查而提供血清的人。对这些血清进行了针对巨细胞病毒（Ad169株）的补体结合抗体滴定。838份血清中有352份（41%）显示出显著的抗体滴度。该病毒感染的发生率在11至20岁年龄组中为26%，在50岁以上年龄组中为59%。几何平均滴度（GMT）在11至20岁年龄组和50岁以上年龄组中最高（22），表明这两个年龄组存在活跃的病毒感染。除了21至30岁年龄组和50岁以上年龄组外，所有年龄组女性的GMT也显著更高，这表明活跃的病毒感染在女性中更为常见。