Huang Yu-Chen, Huang Sheng-Jean, Ko Wen-Je
Department of Surgery, National Taiwan University Hospital, 7 Chung-Shan S. Road, Taipei, Taiwan.
Intensive Care Med. 2009 May;35(5):810-5. doi: 10.1007/s00134-009-1452-1. Epub 2009 Mar 12.
To better understand events related to going home to die (GHTD) from the intensive care unit (ICU), with the hope that this information might improve the palliative care of ICU patients.
This retrospective observational study was performed at a tertiary medical center-the National Taiwan University Hospital. All surgical ICU mortality cases between 1 January 2003 and 31 December 2007 were included in this study.
The rate of GHTD from the ICU declined annually, but has reached a plateau of around 25% in recent years. Multivariate logistic regression analysis found independently significant factors associated with GHTD, including older age (OR: 1.013; P = 0.001), married status (OR: 2.128; P < 0.001), lower educational level (OR: 1.799; P = 0.001), and lack of DNR consent (OR: 1.499; P = 0.006). When treatment intensity was compared on the date of death, GHTD patients in general received more treatments and diagnostic procedures than those who died in the ICU. Univariate analysis showed that GHTD patients received significantly more advanced antibiotics, more chest radiography, greater use of sedatives, greater use of analgesics, and more transfusions, but less FiO(2) and mechanical circulatory support than patients who died in the ICU. CO NCLUSION: GHTD from the ICU is a special phenomenon in the Chinese cultural area, representing a cultural tradition rather than a form of palliative care.
为了更好地了解重症监护病房(ICU)中与回家离世(GHTD)相关的事件,希望这些信息能改善ICU患者的姑息治疗。
这项回顾性观察研究在一家三级医疗中心——台湾大学附属医院进行。纳入了2003年1月1日至2007年12月31日期间所有外科ICU的死亡病例。
ICU中GHTD的发生率逐年下降,但近年来已达到约25%的稳定水平。多因素逻辑回归分析发现与GHTD相关的独立显著因素,包括年龄较大(OR:1.013;P = 0.001)、已婚状态(OR:2.128;P < 0.001)、教育水平较低(OR:1.799;P = 0.001)以及未签署放弃心肺复苏同意书(OR:1.499;P = 0.006)。在死亡日期比较治疗强度时,一般来说,GHTD患者比在ICU死亡的患者接受了更多的治疗和诊断程序。单因素分析显示,GHTD患者比在ICU死亡的患者接受了显著更多的高级抗生素、更多的胸部X光检查、更多地使用镇静剂、更多地使用镇痛药以及更多的输血,但接受的吸氧浓度(FiO₂)和机械循环支持较少。结论:ICU中的GHTD是中国文化区域的一种特殊现象,代表一种文化传统而非姑息治疗的一种形式。