Hou Y P
Department of Forensic Genetics, School of Basic Science and Forensic Medicine, Sichuan University (West China University of Medical Sciences), Ren Min Nan Lu 3-17, Chengdu 610041, Sichuan, PR China.
Leg Med (Tokyo). 2009 Apr;11 Suppl 1:S103-5. doi: 10.1016/j.legalmed.2009.02.019. Epub 2009 Mar 17.
In the field of forensic genetics, essential developmental impulses come from the advances of the molecular biology and human genome projects. This paper overviews existing technologies for forensic genetics in China and gives a perspective of forensic DNA analysis. In China, work has been done in the development of blood group serology of the conventional markers. Forensic scientists in China also contributed to the progress of DNA analysis by the validation of numerous test methods and by optimization of these methods. During these years, forensic DNA analysis in China has experienced tremendous progress towards development of robust, efficient and precise protocols, including the development of short tandem repeat analysis, mitochondrial DNA and Y-chromosome analysis. Forensic scientists are constantly looking for new methods to further improve DNA typing. Therefore, this paper also focuses on emerging new technologies in China, which represent an interest for forensic genetics.
在法医遗传学领域，重要的发展动力来自分子生物学和人类基因组计划的进展。本文概述了中国法医遗传学的现有技术，并对法医DNA分析进行了展望。在中国，传统标记物血型血清学的发展已取得一定成果。中国的法医科学家还通过验证众多检测方法并对这些方法进行优化，为DNA分析的进展做出了贡献。这些年来，中国的法医DNA分析在开发强大、高效和精确的方案方面取得了巨大进展，包括短串联重复序列分析、线粒体DNA和Y染色体分析的发展。法医科学家们一直在寻找新方法以进一步改进DNA分型。因此，本文还关注了中国的新兴技术，这些技术对法医遗传学具有重要意义。
