中国云南怒族群体中10个X染色体短串联重复序列（X-STR）基因座的等位基因频率。

Allele frequencies for 10 X-STR loci in Nu population of Yunnan, China.

作者信息

Gao Shuhui, Qiao Ke, Rakha Allah, Lai Jianghua, Li Shengbin

机构信息

The State Key Laboratory of Ministry of Health for Forensic Sciences, Medical College of Xi'an Jiaotong University, Xi'an 710061, PR China.

出版信息

Leg Med (Tokyo). 2007 Sep;9(5):284-6. doi: 10.1016/j.legalmed.2007.03.002. Epub 2007 Jun 13.

DOI:10.1016/j.legalmed.2007.03.002

PMID:17569570

Abstract

More recently, forensic interest has focused on X-chromosomal markers and which are especially useful in paternity cases with daughters. Genetic polymorphism studies at 10 short tandem repeat (STR) loci on the X-chromosome (DXS6804, DXS6799, DXS8378, DXS7130, DXS7132, HPRTB, DXS7133, DXS7423, DXS101 and DXS6789) were carried out in Yunnan Nu population of China. We aimed at increase in pool of forensically relevant data for allele distribution and frequency of X-chromosomal STRs. Statistical analysis and forensic efficiency data show no deviations from Hardy-Weinberg equilibrium.

摘要

最近，法医学的关注点集中在X染色体标记上，这些标记在涉及女儿的亲子鉴定案件中特别有用。在中国云南怒族人群中，对X染色体上的10个短串联重复序列（STR）位点（DXS6804、DXS6799、DXS8378、DXS7130、DXS7132、HPRTB、DXS7133、DXS7423、DXS101和DXS6789）进行了基因多态性研究。我们旨在增加与法医学相关的X染色体STR等位基因分布和频率的数据储备。统计分析和法医学效率数据表明，该群体符合哈迪-温伯格平衡。