Ding Zhenhua, Yang Jin, Wang Ting, Shen Zongxuan, Zhang Yawen
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Soochow University, Suzhou 215123, China.
Chem Commun (Camb). 2009 Feb 7(5):571-3. doi: 10.1039/b818257d. Epub 2008 Dec 19.
The dynamic kinetic resolution of beta-keto sulfones was achieved via asymmetric transfer hydrogenation using (S,S)-RuClN-(tosyl)-1,2-diphenylethylenediamine in the presence of formic acid and triethylamine afforded the desired products in good yield with up to >99 : 1 dr and high ee up to >99%.
在甲酸和三乙胺存在下，使用(S,S)-RuClN-(对甲苯磺酰基)-1,2-二苯基乙二胺通过不对称转移氢化实现了β-酮砜的动态动力学拆分，以良好的产率得到了所需产物，非对映体比例高达>99:1，对映体过量值高达>99%。
