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利用芳烃交换直接形成键合的钌(II)催化剂。

Direct formation of tethered Ru(II) catalysts using arene exchange.

机构信息

Department of Chemistry, The University of Warwick , Coventry, CV4 7AL, U.K.

出版信息

Org Lett. 2013 Oct 4;15(19):5110-3. doi: 10.1021/ol4024979. Epub 2013 Sep 26.

DOI:10.1021/ol4024979
PMID:24070028
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3856772/
Abstract

An 'arene exchange' approach has been successfully applied for the first time to the synthesis of Ru(II)-based 'tethered' reduction catalysts directly from their ligands in one step. This provides an alternative method for the formation of known complexes, and a route to a series of novel complexes. The novel complexes are highly active in both asymmetric transfer and pressure hydrogenation of ketones.

摘要

一种“芳构环交换”方法已成功首次应用于一步法直接从其配体合成基于 Ru(II)的“束缚”还原催化剂。这为已知配合物的形成提供了一种替代方法，也为一系列新型配合物的合成提供了一种途径。新型配合物在酮的不对称转移氢化和加压氢化中均具有很高的活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/3856772/7604a101665f/ol-2013-024979_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/3856772/4356dea25310/ol-2013-024979_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/3856772/edebd3a0be19/ol-2013-024979_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/3856772/78846f541af7/ol-2013-024979_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/3856772/7604a101665f/ol-2013-024979_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/3856772/4356dea25310/ol-2013-024979_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/3856772/edebd3a0be19/ol-2013-024979_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/3856772/78846f541af7/ol-2013-024979_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/3856772/7604a101665f/ol-2013-024979_0002.jpg

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