Trattnig S, Domayer S, Welsch G W, Mosher T, Eckstein F
MR Centre of Excellence, Department of Radiology, Medical University Vienna, Vienna, Austria.
Eur Radiol. 2009 Jul;19(7):1582-94. doi: 10.1007/s00330-009-1352-3. Epub 2009 Mar 13.
Chondral injuries are common lesions of the knee joint, and many patients could benefit from cartilage repair. Widespread cartilage repair techniques require sophisticated noninvasive follow-up using MRI. In addition to the precise morphological assessment of this area of cartilage repair, the cartilage's biochemical constitution can be determined using biochemical MRI techniques. The combination of the clinical outcome after cartilage repair together with the morphological and biochemical description of the cartilage repair tissue as well as the surrounding cartilage can lead to an optimal follow-up evaluation. The present article on MR imaging techniques of cartilage repair focuses on morphological description and scoring using techniques from conventional 2D through advanced isotropic 3D MRI sequences. Furthermore the ultrastructure of the repair tissue and the surrounding cartilage is evaluated in-vivo by biochemical T1-delayed gadolinium enhanced MRI of cartilage (dGEMRIC), T2 relaxation, and diffusion-weighted imaging techniques.
软骨损伤是膝关节的常见病变，许多患者可从软骨修复中获益。广泛应用的软骨修复技术需要使用MRI进行复杂的无创随访。除了对软骨修复区域进行精确的形态学评估外，还可使用生化MRI技术确定软骨的生化组成。软骨修复后的临床结果与软骨修复组织以及周围软骨的形态学和生化描述相结合，可实现最佳的随访评估。本文关于软骨修复的MR成像技术着重于使用从传统二维到先进各向同性三维MRI序列的技术进行形态学描述和评分。此外，通过软骨生化T1延迟钆增强MRI（dGEMRIC）、T2弛豫和扩散加权成像技术在体内评估修复组织和周围软骨的超微结构。
