Bivalacqua Trinity J, Pierorazio Phillip M, Su Li-Ming
James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institution, Baltimore, MD, United States.
Surg Oncol. 2009 Sep;18(3):233-41. doi: 10.1016/j.suronc.2009.02.009. Epub 2009 Mar 14.
As advances in the understanding of prostatic anatomy led to improvements in functional and oncologic outcomes after prostatectomy of the past few decades, advances in technology and surgical technique have made minimally-invasive prostate surgery a reality. Today patients diagnosed with clinically localized prostate cancer have more surgical treatment options than in the past including open, laparoscopic and robot-assisted laparoscopic radical prostatectomy. Advantages and disadvantages exist for each modality and lead to subtle differences in the technical execution of the procedure. Evidence from centers of excellence and from experienced surgeons demonstrates that both laparoscopic and robotic-assisted laparoscopic radical prostatectomy appear to be comparable to outcomes achieved with open radical retropubic prostatectomy series. Individual surgeon skill, experience and clinical judgment are likely the stronger predictors of outcome rather than the technique chosen. However, learning curves, oncologic outcomes and cost-efficacy remain important considerations in the dissemination of minimally-invasive prostate surgery. A greater appreciation of the periprostatic anatomy and further modification of surgical technique will result in continued improvement in functional outcomes and oncological control for patients undergoing radical prostatectomy, whether by open or minimally-invasive surgery.
在过去几十年里,随着对前列腺解剖结构认识的不断进步,前列腺切除术后的功能和肿瘤学治疗效果得到了改善,而技术和手术技巧的进步使微创前列腺手术成为现实。如今,被诊断为临床局限性前列腺癌的患者比过去有更多的手术治疗选择,包括开放式、腹腔镜和机器人辅助腹腔镜根治性前列腺切除术。每种手术方式都有其优缺点,这导致了手术操作技术上的细微差异。来自卓越中心和经验丰富的外科医生的证据表明,腹腔镜和机器人辅助腹腔镜根治性前列腺切除术的效果似乎与开放式耻骨后根治性前列腺切除术系列相当。个体外科医生的技能、经验和临床判断可能是比所选择的技术更强的预后预测因素。然而,学习曲线、肿瘤学治疗效果和成本效益仍然是微创前列腺手术推广过程中的重要考虑因素。无论是开放式手术还是微创手术,对前列腺周围解剖结构的更深入理解和手术技术的进一步改进,将使接受根治性前列腺切除术的患者的功能预后和肿瘤学控制得到持续改善。