Peking University Third Hospital, Beijing, China.
Stud Mycol. 2008;61:131-6. doi: 10.3114/sim.2008.61.13.
Coniosporium epidermidis sp. nov. is described from a superficial skin lesion with blackish discolouration in an 80-yr-old Chinese patient. The species produces dark, thick-walled, inflated, reluctantly liberating arthroconidia without longitudinal septa. Sequences of the ribosomal operon, as well as of the translation elongation factor 1-alpha support its novelty. The species is found in a lineage basal to the order Chaetothyriales, amidst relatives from rock, but also species repeatedly isolated from human skin and nails and eventually causing mild cutaneous infections. Coniosporium epidermidis is consistently found on humans, either asymptomatic or symptomatic. The species indicates a change of life style towards human pathogenicity, which is a recurrent type of ecology in derived Chaetothyriales. Superficial and cutaneous infection by melanized fungi is a new category in dermatology.
表皮康氏孢菌被描述为一种从 80 岁中国患者的皮肤浅部病变中分离出来的真菌，该病变表现为黑色变色。该种产生深色、厚壁、膨胀、难以释放的具横隔膜的节孢子。核糖体操纵子和翻译延伸因子 1-α的序列支持其新颖性。该种位于 Chaetothyriales 目之下的一个分支中，与来自岩石的亲缘种相邻，但也与反复从人类皮肤和指甲中分离出来的种有关，最终可导致轻度皮肤感染。表皮康氏孢菌在人类中一直存在，无论是无症状还是有症状。该种表明生活方式向人类致病性发生了变化，这是衍生出的 Chaetothyriales 中一种反复出现的生态类型。黑真菌引起的皮肤和皮肤感染是皮肤科中的一个新类别。
