Department of Physiology, Kaunas University of Medicine, Kaunas, Lithuania.
Phytother Res. 2009 Oct;23(10):1474-8. doi: 10.1002/ptr.2805.
The aim of this study was to examine the effect of purple coneflower (Echinacea purpurea L. Moench) on the prostate gland of rats using an experimental model of benign prostate hyperplasia (BPH). The animals were administered 50 mg/kg of extract preparation for 4 and 8 weeks and the prostate mass and structural degenerative changes were evaluated in the course of the experiment. The administration of E. purpurea extract to rats with hyperplasia for 4 and 8 weeks gradually and significantly reduced the prostate mass and reversed the degenerative changes in the structure of the prostate gland. The present investigation suggests extract of purple coneflower prevents the development of BPH.
本研究旨在通过良性前列腺增生（BPH）的实验模型，研究紫锥菊（Echinacea purpurea L. Moench）对大鼠前列腺的影响。动物给予 50mg/kg 的提取物制剂 4 周和 8 周，实验过程中评估前列腺质量和结构退行性变化。紫锥菊提取物对增生大鼠给药 4 周和 8 周，逐渐显著降低前列腺质量，并逆转前列腺结构的退行性变化。本研究表明紫锥菊提取物可预防 BPH 的发生。
