从AKR小鼠和新西兰小鼠中分离并比较鼠白血病病毒相关糖蛋白
Isolation and comparison of murine leukemia virus-related glycoproteins from AKR and New Zealand mice.
作者信息
Kennel S J
出版信息
J Virol. 1977 Apr;22(1):168-74. doi: 10.1128/JVI.22.1.168-174.1977.
The major glycoprotein (gp70) of murine leukemia virus occurs free of virus in the serum and body fluids of certain strains of mice. These glycoproteins were isolated from New Zealand Black mouse (NZB) ascites fluid and from AKR and New Zealand White mouse (NZW) serum by immunoaffinity chromatography and were compared by immunological tests and peptide mapping. Glycoproteins gp70-NZB and gp70-NZW were indistinguishable by all criteria tested and were more closely related to gp70 from Moloney leukemia virus than was gp70-AKR.
鼠白血病病毒的主要糖蛋白（gp70）在某些品系小鼠的血清和体液中以无病毒形式存在。这些糖蛋白通过免疫亲和层析从新西兰黑鼠（NZB）腹水以及AKR和新西兰白鼠（NZW）血清中分离出来，并通过免疫测试和肽图谱分析进行比较。糖蛋白gp70-NZB和gp70-NZW在所有测试标准下都无法区分，并且与莫洛尼白血病病毒的gp70相比，它们与gp70-AKR的关系更为密切。
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