静脉注射氧氟沙星意外过量，结局良好。
Accidental overdose of intravenous ofloxacin with benign outcome.
作者信息
Kohler R B, Arkins N, Tack K J
机构信息
Department of Medicine, Indiana University School of Medicine, Indianapolis 46202.
出版信息
Antimicrob Agents Chemother. 1991 Jun;35(6):1239-40. doi: 10.1128/AAC.35.6.1239.
Abstract
A patient accidentally received approximately 3 g of ofloxacin intravenously. She experienced only moderately severe central nervous system symptoms, which resolved within 9 h. The peak serum ofloxacin level was 39.3 micrograms/ml, approximately seven times the usual peak level. Ofloxacin may possess a considerable safety margin in humans.
摘要
一名患者意外静脉注射了约3克氧氟沙星。她仅出现了中度严重的中枢神经系统症状，这些症状在9小时内得到缓解。血清中氧氟沙星的峰值水平为39.3微克/毫升，约为通常峰值水平的7倍。氧氟沙星在人体中可能具有相当大的安全范围。
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