Neri Piergiorgio, Salvolini Simone, Giovannini Alfonso, Mariotti Cesare
Eye Clinic, Azienda Ospedaliero Universitaria, Ospedali Riuniti di Ancona, Ancona, Italy. doctor
Ocul Immunol Inflamm. 2009 Jan-Feb;17(1):36-40. doi: 10.1080/09273940802491876.
To report on 3 cases of retinal vasculitis associated with asymptomatic Gardnerella vaginalis (GV) infection.
Review of 3 consecutive patients who presented with central retinal vasculitis without signs or symptoms of systemic disease. The vasculitis involved the central branches of the retinal vessels bilaterally and was steroid-dependent.
During treatment, patients developed clinically significant vaginitis, which the gynecologist considered to be exacerbated by the steroid treatment, leading to its withdrawal. All 3 vaginal specimens were positive for GV. Antibiotic susceptibility testing led to administration of oral ampicillin (2 g/day for 10 days), which resolved both the vaginal infection and the retinal vasculitis.
Idiopathic retinal vasculitis can be triggered by several agents. In this case series, GV was associated with retinal vasculitis, which was resolved by oral ampicillin. GV infection may be one of a number of triggers of retinal vasculitis. Appropriate treatment and full resolution of ocular inflammation requires exclusion of possible underlying infections.
报告3例与无症状阴道加德纳菌（GV）感染相关的视网膜血管炎病例。
回顾3例连续出现中心性视网膜血管炎且无全身疾病体征或症状的患者。血管炎累及双侧视网膜血管的中央分支，且依赖类固醇治疗。
治疗期间，患者出现具有临床意义的阴道炎，妇科医生认为类固醇治疗使其加重，导致停药。所有3份阴道标本GV检测均为阳性。抗生素敏感性试验导致给予口服氨苄西林（2克/天，共10天），这使阴道感染和视网膜血管炎均得到缓解。
特发性视网膜血管炎可由多种因素引发。在本病例系列中，GV与视网膜血管炎相关，口服氨苄西林可使其缓解。GV感染可能是视网膜血管炎的多种触发因素之一。适当的治疗和眼部炎症的完全缓解需要排除可能的潜在感染。
