No sensory neuropathy during pyridoxine treatment in homocystinuria.
作者信息
Mpofu C, Alani S M, Whitehouse C, Fowler B, Wraith J E
机构信息
Willink Biochemical Genetics Unit, Royal Manchester Children's Hospital.
出版信息
Arch Dis Child. 1991 Sep;66(9):1081-2. doi: 10.1136/adc.66.9.1081.
Abstract
Seventeen patients with cystathionine synthase deficiency homocystinuria were examined clinically and neurophysiologically for evidence of sensory neuropathy. All had received high dose pyridoxine (vitamin B-6) for many years. Absence of neurological disturbance in all cases suggests long term treatment with pyridoxine in the dosages used in homocystinuric patients is not harmful.
摘要
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