基质金属蛋白酶在皮肤衰老中的作用。
Role of matrix metalloproteinases in skin ageing.
作者信息
Sárdy Miklós
机构信息
Department of Dermatology and Allergology, Ludwig-Maximilians University, München, Germany.
出版信息
Connect Tissue Res. 2009;50(2):132-8. doi: 10.1080/03008200802585622.
PMID:19296304
Abstract
Matrix metalloproteinases are a family of ubiquitous endopeptidases playing a role in many different physiological and pathological processes in the skin. They are also involved in cutaneous ageing. This review summarizes the features and regulation of these enzymes and presents an overview of the molecular mechanisms of both intrinsic and extrinsic skin ageing presents. The role of matrix metalloproteinases in skin ageing is discussed in detail.
摘要
基质金属蛋白酶是一类普遍存在的内肽酶，在皮肤的许多不同生理和病理过程中发挥作用。它们也参与皮肤老化过程。本文综述了这些酶的特性和调控，并概述了皮肤内在老化和外在老化的分子机制。详细讨论了基质金属蛋白酶在皮肤老化中的作用。
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