从苦皮藤中分离得到的三种新型杀虫倍半萜吡啶生物碱。

Three new insecticidal sesquiterpene pyridine alkaloids from Celastrus angulatus.

作者信息

Zhiqing Ji, Qidong Zhang, Baojun Shi, Shaopeng Wei, Mingan Wang, Wenjun Wu

机构信息

Department of Plant Protection, Northwestern Agricultural University, Yangling, Shaanxi, People's Republic of China.

出版信息

Nat Prod Res. 2009;23(5):470-8. doi: 10.1080/14786410802086217.

DOI:10.1080/14786410802086217

PMID:19296392

Abstract

Three new sesquiterpene pyridine alkaloids with a beta-dihydroagarofuran sesquiterpene skeleton, celangulatin G(1), H(2) and I(3), and one known alkaloid 4 were isolated from the middle-polar extracts of the root bark of Celastrus angulatus by bioassay-guided separation. Their chemical structures were elucidated mainly by the analyses of the MS and NMR spectral data. Celangulatin G(1), H(2), I(3) and 4 showed KD(50) against Mythimna separata were 849.61, 80.24, 96.29 and 50.98 microg g(-1), respectively.

摘要

通过生物活性导向分离法，从南蛇藤根皮的中极性提取物中分离出三种具有β-二氢沉香呋喃倍半萜骨架的新型倍半萜吡啶生物碱，即南蛇藤素G（1）、H（2）和I（3），以及一种已知生物碱4。它们的化学结构主要通过质谱和核磁共振光谱数据进行解析。南蛇藤素G（1）、H（2）、I（3）和4对粘虫的半数致死剂量（KD50）分别为849.61、80.24、96.29和50.98 μg g-1。