Seales D, Greer M
Department of Neurology, University of Florida College of Medicine, Gainesville.
Arch Neurol. 1991 Oct;48(10):1086-8. doi: 10.1001/archneur.1991.00530220108029.
A 50-year-old woman developed acute hemorrhagic leukoencephalitis approximately 7 days after the onset of a benign respiratory infection. Mycoplasmal pneumonia was suspected because of Coomb's positive hemolysis, cold agglutinins, and sensitivity to erythromycin base but was not proved. Acute hemorrhagic leukoencephalitis was demonstrated by brain biopsy 24 hours after admission. The patient recovered without lasting sequelae following reduction of increased intracranial pressure by mannitol, hyperventilation, and phenobarbital and prolonged immunosuppression by plasmapheresis, steroids, and cyclophosphamide.
一名50岁女性在良性呼吸道感染发病约7天后患上急性出血性白质脑炎。由于库姆斯试验阳性溶血、冷凝集素以及对红霉素碱敏感，怀疑为支原体肺炎，但未得到证实。入院24小时后经脑活检确诊为急性出血性白质脑炎。通过甘露醇、过度换气和苯巴比妥降低颅内压升高，并通过血浆置换、类固醇和环磷酰胺进行长期免疫抑制后，患者康复且无持久后遗症。
