Mohandas Naveen, Balasubramanian R, Prasad Shiva B N
Department of Medicine, Kasturba Medical College, Manipal, Karnataka, India.
Trop Doct. 2009 Apr;39(2):123-4. doi: 10.1258/td.2008.070446.
Human brucellosis is caused by one of the three species of Brucella: Brucella mellitensis, B. abortus, and B. suis. Worldwide, the incidence of human brucellosis ranges from <0.01 to >200 per 100,000 population. Cardiovascular complications occur in <2%, but accounts for most of the mortality. Brucella endocarditis usually involves normal native aortic valves in 75% of cases. A combination of antibiotics and valve replacement is the most acceptable treatment. So far only 15 adult cases have been reported as having been cured with medical therapy alone. We report another case treated successfully with antibiotics alone.
马尔他布鲁氏菌、流产布鲁氏菌和猪布鲁氏菌。在全球范围内，人类布鲁氏菌病的发病率为每10万人中<0.01至>200例。心血管并发症的发生率<2%，但却是导致死亡的主要原因。布鲁氏菌性心内膜炎在75%的病例中通常累及正常的原生主动脉瓣。抗生素与瓣膜置换相结合是最可接受的治疗方法。到目前为止，仅有15例成年病例报告称仅通过药物治疗就得以治愈。我们报告了另一例仅用抗生素成功治疗的病例。
