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口腔扁平苔藓患者舌背的形态计量学分析

Morphometric analysis of the dorsum linguae in patients with Oral Lichen Planus.

作者信息

Bermejo-Fenoll Ambrosio, López-Jornet Pía, Camacho-Alonso Fabio, Saura-Ingles Antonio, Panchon-Ruiz Alfonso

机构信息

Department of Oral Medicine, Faculty of Medicine and Odontology, University of Murcia, Spain.

出版信息

Med Oral Patol Oral Cir Bucal. 2009 Aug 1;14(8):e388-92.

PMID:19300352
Abstract

OBJECTIVE

Morphometric study of the dorsum linguae in patients with Oral Lichen Planus (OLP).

MATERIAL AND METHOD

In 236 patients with a clinicopathologic diagnosis of OLP, 111 were found to have involvement of the dorsum linguae. For the purposes of the study, 41 of these cases were used, due to the availability of photographic records fulfilling quality conditions according to objective criteria. The experimental variable was defined as the proportion of affected dorsum linguae measured and calculated using the MIP4(R) computer software.

RESULTS

In 236 patients with OLP, the mucosa of the dorsum linguae was affected in 47.6% of the cases (total 111). The proportion of affected area was studied in 41 of these cases, 8 men (19.5%) and 33 women (80.5%). In 73% of these cases, the affected area was less than 50% of the total surface of the dorsum linguae. There were no statistically significant differences (p=0.495) in relation to age and proportion of lingual surface affected. On the other hand, significant statistical differences were found between the period of disease evolution and area of lingual involvement (p=0.044).

CONCLUSION

Lingual involvement is frequent in patients with OLP, and manifests as de-papillate areas to the left and right of the median sulcus of tongue (occasionally linked by an isthmus) and having a certain " butterfly wing" symmetry.

摘要

目的

对口腔扁平苔藓(OLP)患者舌背进行形态计量学研究。

材料与方法

在236例经临床病理诊断为OLP的患者中,发现111例舌背受累。为进行本研究,由于有符合客观标准质量条件的摄影记录,使用了其中41例。实验变量定义为使用MIP4(R)计算机软件测量和计算的受累舌背比例。

结果

在236例OLP患者中,47.6%的病例(共111例)舌背黏膜受累。在其中41例病例中研究了受累面积比例,男性8例(19.5%),女性33例(80.5%)。在这些病例中,73%的受累面积小于舌背总面积的50%。在年龄与舌面受累比例方面无统计学显著差异(p = 0.495)。另一方面,在疾病演变期与舌部受累面积之间发现了显著的统计学差异(p = 0.044)。

结论

OLP患者舌部受累很常见,表现为舌中沟左右的乳头缺失区域(偶尔由峡部相连),具有一定的“蝴蝶翼”对称性。

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