Chaturvedi Arvind K, Botch Sabra R, Canfield Dennis V, Forster Estrella M
Bioaeronautical Sciences Research Laboratory, Aerospace Medical Research Division, Civil Aerospace Medical Institute, Federal Aviation Administration, U.S. Department of Transportation, Oklahoma City, OK 73125-5066, USA.
J Forensic Sci. 2009 May;54(3):715-20. doi: 10.1111/j.1556-4029.2009.01011.x. Epub 2009 Mar 16.
During aviation accident investigations, vitreous fluid and urine samples from pilot fatalities are analyzed for glucose and blood for hemoglobin A(1c) (HbA(1c)) to monitor diabetic pilots and to discover other pilots with undiagnosed/unreported diabetes. The prevalence of elevated glucose concentrations in fatally injured pilots was evaluated by searching the Civil Aerospace Medical Institute's Toxicology Database for the period 1998-2005. Out of 1335 pilots involving 363 vitreous fluid, 365 urine, and 607 vitreous fluid and urine analyses, 43 pilots had elevated glucose in vitreous fluid (>125 mg/dL) and/or in urine (>100 mg/dL). Of the 20 pilots whose blood samples were analyzed, nine had >6% HbA(1c)--four were known diabetics, and five were unknown diabetics. Urinary glucose levels were elevated in all 13 known hyperglycemic pilots. A considerable number of pilots (30 of 43) had elevated glucose and HbA(1c) (5 of 20), suggesting undiagnosed/unreported diabetic conditions.
在航空事故调查过程中，会对遇难飞行员的玻璃体液和尿液样本进行葡萄糖分析，并对血液进行糖化血红蛋白A1c（HbA1c）检测，以监测糖尿病飞行员，并发现其他未被诊断/未报告患有糖尿病的飞行员。通过检索民用航空医学研究所1998 - 2005年期间的毒理学数据库，评估了遇难飞行员中血糖浓度升高的患病率。在涉及363份玻璃体液、365份尿液以及607份玻璃体液和尿液分析的1335名飞行员中，有43名飞行员的玻璃体液葡萄糖浓度（>125mg/dL）和/或尿液葡萄糖浓度（>100mg/dL）升高。在对血液样本进行分析的20名飞行员中，有9名的HbA1c>6%——其中4名是已知糖尿病患者，5名是未知糖尿病患者。所有13名已知血糖过高的飞行员尿液葡萄糖水平均升高。相当数量的飞行员（43名中的30名）血糖和HbA1c升高（20名中的5名），提示存在未被诊断/未报告的糖尿病情况。
