Watson Ralph E, Karnchanasorn Rudruidee, Gossain Ved V
Department of Medicine, Hypertension Clinic, College of Human Medicine, Michigan State University, Clinical Center, East Lansing, MI 48824, USA.
J Clin Hypertens (Greenwich). 2009 Mar;11(3):148-52. doi: 10.1111/j.1751-7176.2009.00088.x.
Asian/Pacific Islander Americans (APIAs) are the fastest growing population in the United States by percentage. Hypertension is common and increases cardiovascular risk to a great extent in this population. The medical problems of this group are being increasingly encountered by US physicians. Many gene mutations associated with hypertension are more common in Asians. The significance of these polymorphisms in the pathogenesis of hypertension in APIAs is unclear. The percentage of APIAs who are aware, treated, and controlled is small. There may be some differences in the responses to antihypertensive medications between APIAs and whites. The results of human studies on the effect of drinking of tea on blood pressure in different groups are conflicting. Cough associated with angiotensin-converting enzyme inhibitor therapy may be more common in APIAs than in whites. There is a need for more education of APIAs regarding hypertension and for more effective treatment of hypertension by the physicians caring for this population.
亚太裔美国人(APIAs)是美国人口中按百分比计算增长最快的群体。高血压在该群体中很常见,并且在很大程度上增加了心血管疾病风险。美国医生越来越多地遇到这个群体的医疗问题。许多与高血压相关的基因突变在亚洲人中更为常见。这些多态性在亚太裔美国人高血压发病机制中的意义尚不清楚。知晓、接受治疗并得到控制的亚太裔美国人比例很小。亚太裔美国人和白人对抗高血压药物的反应可能存在一些差异。关于饮茶对不同群体血压影响的人体研究结果相互矛盾。与血管紧张素转换酶抑制剂治疗相关的咳嗽在亚太裔美国人中可能比在白人中更常见。需要对亚太裔美国人进行更多关于高血压的教育,并让照顾该群体的医生更有效地治疗高血压。