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完成疼痛康复计划的慢性非恶性疼痛患者的药物成本降低:入院、出院及6个月随访药物成本的前瞻性分析

Reduction in medication costs for patients with chronic nonmalignant pain completing a pain rehabilitation program: a prospective analysis of admission, discharge, and 6-month follow-up medication costs.

作者信息

Cunningham Julie L, Rome Jeffrey D, Kerkvliet Jennifer L, Townsend Cynthia O

机构信息

Department of Pharmacy, Mayo Clinic College of Medicine, Rochester, Minnesota 55902, USA.

出版信息

Pain Med. 2009 Jul-Aug;10(5):787-96. doi: 10.1111/j.1526-4637.2009.00582.x. Epub 2009 Mar 19.

Abstract

OBJECTIVE

Chronic nonmalignant pain (CNMP) is both a prevalent and a costly health problem in our society. Pain rehabilitation programs have been shown to provide cost-effective treatment. A treatment goal for some rehabilitation programs is reduction in the use of pain-related medication. Medication costs savings from pain rehabilitation programs have not been analyzed in previous studies.

DESIGN

This prospective cohort study of 186 patients with CNMP addresses the costs of medications at admission to a 3-week outpatient pain rehabilitation program, at discharge, and at 6-month follow-up. Medication use was determined through a detailed pharmacist interview with patients at admission and discharge. Patients were sent questionnaires 6 months after program completion, which obtained current medication information.

RESULTS

Statistically significant medication cost savings were seen for program completers at discharge and at 6-month follow-up (P < 0.05). The mean (standard deviation) daily prescription medication cost reduction from admission to discharge was $9.31 ($12.70) using the average wholesale price of medications. From the original study cohort, 121 patients completed the 6-month follow-up survey. The mean daily prescription medication cost savings from admission to 6-month follow-up was $6.68 ($14.40).

CONCLUSION

Patients benefited from significant medication cost savings at the completion of the 3-week outpatient pain rehabilitation program and maintained significant savings after 6 months. This study adds to the current literature on the economic value of comprehensive pain rehabilitation programs.

摘要

目的

慢性非恶性疼痛(CNMP)在我们的社会中是一个普遍且成本高昂的健康问题。疼痛康复项目已被证明能提供具有成本效益的治疗。一些康复项目的治疗目标是减少与疼痛相关药物的使用。以往研究尚未分析疼痛康复项目带来的药物成本节省情况。

设计

这项对186名CNMP患者的前瞻性队列研究,探讨了在参加为期3周的门诊疼痛康复项目入院时、出院时以及6个月随访时的药物成本。通过药剂师在患者入院和出院时与他们进行详细访谈来确定药物使用情况。在项目完成6个月后向患者发送问卷,以获取当前药物信息。

结果

在出院时和6个月随访时,项目完成者在药物成本方面有统计学意义上的显著节省(P < 0.05)。使用药物的平均批发价格,从入院到出院,每日处方药物成本平均(标准差)降低了9.31美元(12.70美元)。在最初的研究队列中,121名患者完成了6个月的随访调查。从入院到6个月随访,每日处方药物成本平均节省6.68美元(14.40美元)。

结论

患者在完成为期3周的门诊疼痛康复项目后,在药物成本方面有显著节省,并且在6个月后仍保持显著节省。这项研究为当前关于综合疼痛康复项目经济价值的文献增添了内容。

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