Ajlani H, Meddeb N, Sahli H, Sellami S
Service de rhumatologie, hôpital La-Rabta, 1007 Tunis, Tunisia.
Rev Pneumol Clin. 2009 Feb;65(1):16-22. doi: 10.1016/j.pneumo.2008.09.014. Epub 2009 Jan 6.
Erasmus' syndrome involves the association of systemic scleroderma and exposure to silica particles with or without silicosis. The authors report the observation of a miner with a history of professional silicosis resulting in pulmonary fibrosis. Twenty-five years later, the patient consulted for dysphagia associated with inflammatory arthralgia, cutaneous sclerosis extended to the face and limbs, sclerodactyly and Raynaud's phenomenon. The diagnosis of scleroderma was confirmed and Erasmus' syndrome was retained.
伊拉斯谟综合征包括系统性硬化症与接触二氧化硅颗粒(无论是否伴有矽肺)的关联。作者报告了一名有职业性矽肺病史并导致肺纤维化的矿工的病例。25年后,该患者因吞咽困难伴炎性关节痛、皮肤硬化扩展至面部和四肢、指硬皮病和雷诺现象前来就诊。硬皮病的诊断得到证实,并确诊为伊拉斯谟综合征。