Center for Eating Disorders Ursula, Leidschendam, The Netherlands.
Int J Eat Disord. 2010 Mar;43(2):130-8. doi: 10.1002/eat.20676.
To study the course and outcome of patients with eating disorder detected in primary care.
General practitioners (GP's) provided information on the course and outcome of eating disorders in patients (n = 147) diagnosed with anorexia nervosa (AN) or bulimia nervosa (BN) identified during a Dutch nationwide primary care-based incidence study. The research team determined the outcome based on the data provided by the GP's. The mean duration of the follow-up was 4.8 years.
About 57% of the patients initially diagnosed with AN and 61% of those diagnosed with BN were fully recovered. AN binge/purge subtype (ANBP) demonstrated the most extended median survival time of all diagnostic subgroups (the point at which half of the group has reached full recovery). Diagnostic crossover was low. A younger age at detection predicted recovery at outcome for AN and BN. One patient (AN) died.
The results of this study on differences in outcome and low crossover support the diagnostic distinction between AN and BN in the DSM-IV. Early detection is of major importance for a favorable outcome.
研究初级保健中发现的饮食障碍患者的病程和转归。
全科医生(GP)提供了在荷兰全国初级保健为基础的发病率研究中诊断为神经性厌食症(AN)或神经性贪食症(BN)的患者(n=147)的病程和转归信息。研究小组根据 GP 提供的数据确定了结果。平均随访时间为 4.8 年。
最初诊断为 AN 的患者中有约 57%和诊断为 BN 的患者中有 61%完全康复。AN 暴食/清除亚型(ANBP)在所有诊断亚组中表现出最长的中位生存时间(即一半患者达到完全恢复的时间点)。诊断交叉较低。检测时年龄较小预测 AN 和 BN 的转归。有一名患者(AN)死亡。
本研究关于结局差异和低交叉的结果支持 DSM-IV 中 AN 和 BN 的诊断区分。早期发现对于良好的结局至关重要。