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新生儿心脏手术后的营养支持。

Nutrition support after neonatal cardiac surgery.

作者信息

Owens Joyce L, Musa Ndidiamaka

机构信息

Medical College of Wisconsin, Pediatrics, Critical Care, 9000 W Wisconsin Ave, Milwaukee, WI 53226, USA.

出版信息

Nutr Clin Pract. 2009 Apr-May;24(2):242-9. doi: 10.1177/0884533609332086.

Abstract

Congenital heart disease is the most common birth defect in the United States, with an estimated frequency of approximately 12-14 of 1000 live births per year. Neonates with congenital heart disease often need palliative or corrective surgery requiring cardiopulmonary bypass during the first weeks of life. The neonate undergoing cardiopulmonary bypass surgery experiences a more profound metabolic response to stress than that seen in older children and adults undergoing surgery. However, compared with older children and adults, the neonate has less metabolic reserves and is extremely vulnerable to the negative metabolic impact induced by stress, which can lead to suboptimal wound healing and growth failure. There are complications associated with the metabolic derangements of neonatal surgery requiring cardiopulmonary bypass, including but not limited to acute renal failure, chylothorax, and neurological dysfunction. This article discusses the importance of nutrition and metabolic support for the neonate undergoing cardiopulmonary bypass and the immediate postoperative nutrition needs of such a patient. Also, this article uses a case study to examine the feeding methodology used at one particular institution after neonatal cardiac surgery. The purpose of the case study is to provide an illustration of the many factors and obstacles that clinicians often face in the provision and timing of nutrition support.

摘要

先天性心脏病是美国最常见的出生缺陷,估计每年每1000例活产中约有12 - 14例患病。患有先天性心脏病的新生儿通常需要在出生后的头几周进行姑息性或矫正性手术,手术需要体外循环。与接受手术的大龄儿童和成人相比,接受体外循环手术的新生儿对压力的代谢反应更为强烈。然而,与大龄儿童和成人相比,新生儿的代谢储备较少,极易受到压力引起的负面代谢影响,这可能导致伤口愈合不佳和生长发育迟缓。体外循环的新生儿手术存在与代谢紊乱相关的并发症,包括但不限于急性肾衰竭、乳糜胸和神经功能障碍。本文讨论了营养和代谢支持对接受体外循环的新生儿的重要性以及此类患者术后即刻的营养需求。此外,本文通过一个案例研究来探讨某一特定机构在新生儿心脏手术后所采用的喂养方法。该案例研究的目的是举例说明临床医生在提供营养支持及其时机方面经常面临的诸多因素和障碍。

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