State Key Laboratory Cultivation Base, China National Optometry Center, Eye Hospital, Wenzhou Medical College, Wenzhou, China.
Eye (Lond). 2010 Jan;24(1):21-8. doi: 10.1038/eye.2009.57. Epub 2009 Mar 27.
To report and discuss the postoperative complications in patients after Densiron 68 intraocular tamponade in the management of complicated retinal detachment with proliferative vitreoretinopathy (PVR).
We presented a prospective interventional non-comparative case series of 27 eyes of 27 consecutive patients. Inclusion criteria were PVR, posterior or inferior retinal breaks, and the patient's inability to posture. Vitreoretinal surgery with Densiron 68 intraocular tamponade was performed in all patients. Complications were recorded at 1 week and 1, 2, and 3 months after Densiron 68 intraocular tamponade and after removal of Densiron 68 endotamponade at same periods.
The most common complication was posterior capsule opacification and cataract development in seven eyes (25.9%) and in two eyes (25%, 2/8), respectively, the second complication was intraocular inflammation in six eyes (22.2%), the third complication was emulsification and dispersion and raised intraocular pressure in five eyes (18.5%), respectively. The success rate with one operation using Densiron 68 was 85.2% and with further surgery 92.5%. Visual acuity improved from mean logMAR of 2.12 (SD= 0.68) to 1.16 (SD=0.84), P=0.0001.
According to the results of this study, postoperative complications did not increase significantly in the vitreoretinal surgery with temporary Densiron 68 intraocular tamponade. Densiron 68 intraocular tamponade is safe and effective in treating complicated retinal detachment.
报告并讨论增生性玻璃体视网膜病变(PVR)复杂性视网膜脱离患者行 Den- siron 68 眼内填充术后的并发症。
本研究为前瞻性、干预性、非对照病例系列研究,共纳入 27 例(27 只眼)连续性患者。纳入标准为 PVR、后极或下方视网膜裂孔和患者无法保持特定体位。所有患者均行玻璃体视网膜手术联合 Den- siron 68 眼内填充。术后 1 周和 1、2、3 个月及取出 Den- siron 68 眼内填充时记录并发症。
7 只眼(25.9%)最常见的并发症是后发性白内障和白内障形成,2 只眼(25%,2/8)分别为第 2 常见的并发症是眼内炎症,6 只眼(22.2%)为第 3 常见的并发症是乳化和弥散以及眼内压升高。单次手术应用 Den- siron 68 的成功率为 85.2%,进一步手术的成功率为 92.5%。视力从平均 logMAR 2.12(SD=0.68)提高到 1.16(SD=0.84),P=0.0001。
根据本研究结果,暂时性 Den- siron 68 眼内填充的玻璃体视网膜手术后,术后并发症并未显著增加。Den- siron 68 眼内填充治疗复杂性视网膜脱离安全有效。