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重硅油填充:多中心经验。

Heavy silicone oil tamponade: a multicentre experience.

机构信息

Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK

Southend University Hospital, Southend, UK.

出版信息

BMJ Open Ophthalmol. 2022 Dec;7(1). doi: 10.1136/bmjophth-2022-001018. Epub 2022 Dec 8.

Abstract

OBJECTIVE

To report multicentred use of the heavy silicone oil Densiron 68 for anatomical reattachment following rhegmatogenous retinal detachment (RRD) repair and its associated complications.

METHODS AND ANALYSIS

Patients from seven vitreoretinal units within the UK that underwent RRD repair with Densiron 68 between January 2015 and December 2019 were identified. Primary outcome measures were primary and final reattachment rate, retained Densiron and failure rate. Secondary outcome measures were duration of tamponade, final visual acuity (VA) and complications of heavy silicone oil.

RESULTS

134 eyes of 134 patients were involved in the study. Primary surgical success was achieved in 48.5%, while a final reattachment rate of 73.4% was observed. The mean duration of Densiron 68 tamponade was 139.5 days. Mean final VA was 1.01 (range 0-2.9). 8 eyes (6.0%) required long-term topical steroids for anterior uveitis, whereas none of the eyes required long-term pressure-lowering treatment. Emulsification rate was 10.7% (6 eyes).

CONCLUSION

This is the largest real-world study on Densiron 68 in the UK. Densiron 68 facilitates tamponade of inferior retinal pathology and may be considered as an option for tamponade of inferior retinal pathologies.

摘要

目的

报告重硅油 Densiron 68 在孔源性视网膜脱离(RRD)修复后解剖复位中的多中心应用及其相关并发症。

方法和分析

确定了 2015 年 1 月至 2019 年 12 月期间在英国的七个玻璃体视网膜单位接受 Densiron 68 治疗的 RRD 修复患者。主要结局指标为原发性和最终复位率、保留的 Densiron 和失败率。次要结局指标为重硅油的填塞持续时间、最终视力(VA)和并发症。

结果

研究共涉及 134 例 134 只眼。初次手术成功率为 48.5%,最终复位率为 73.4%。Densiron 68 填塞的平均持续时间为 139.5 天。平均最终 VA 为 1.01(范围 0-2.9)。8 只眼(6.0%)因前葡萄膜炎需要长期局部皮质类固醇治疗,而无眼需要长期降压治疗。乳化率为 10.7%(6 眼)。

结论

这是英国关于 Densiron 68 的最大真实世界研究。Densiron 68 有利于视网膜下病理的填塞,可被视为填塞视网膜下病理的一种选择。

相似文献

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Heavy silicone oil tamponade: a multicentre experience.重硅油填充:多中心经验。
BMJ Open Ophthalmol. 2022 Dec;7(1). doi: 10.1136/bmjophth-2022-001018. Epub 2022 Dec 8.
2
Primary vitrectomy with Densiron-68 for rhegmatogenous retinal detachment.使用Densiron-68进行原发性玻璃体切除术治疗孔源性视网膜脱离。
Graefes Arch Clin Exp Ophthalmol. 2008 Nov;246(11):1541-6. doi: 10.1007/s00417-008-0894-4. Epub 2008 Jul 11.

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Long-term heavy silicone oil intraocular tamponade.长期大量硅油眼内填充
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